Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function

Chung Amy W.; Crispin Max; Pritchard Laura; Robinson Hannah; Gorny Miroslaw K.; Yu Xiaojie; Bailey-Kellogg Chris; Ackerman Margaret E.; Scanlan Chris; Zolla-Pazner Susan; Alter Galit

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Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function

机译：鉴定可预测单克隆抗体Fc效应子功能的抗体糖基化结构

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Objective: To determine monoclonal antibody (mAb) features that predict fragment crystalizable (Fc)-mediated effector functions against HIV.

机译：目的：确定能够预测可结晶片段（Fc）介导的针对HIV的效应子功能的单克隆抗体（mAb）功能。

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《AIDS》 |2014年第17期|共8页
作者
Chung Amy W.; Crispin Max; Pritchard Laura; Robinson Hannah; Gorny Miroslaw K.; Yu Xiaojie; Bailey-Kellogg Chris; Ackerman Margaret E.; Scanlan Chris; Zolla-Pazner Susan; Alter Galit;
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正文语种 eng
中图分类传染病;
关键词
antibody-dependent cellular cytotoxicity; antibody-dependent cellular phagocytosis; glycan structure; monoclonal antibody;

机译：抗体依赖性细胞毒性;抗体依赖性细胞吞噬作用;聚糖结构;单克隆抗体;
入库时间 2022-08-18 09:58:24

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专利

1. Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function [J] . Chung Amy W., Crispin Max, Pritchard Laura, AIDS . 2014,第17期

机译：鉴定可预测单克隆抗体Fc效应子功能的抗体糖基化结构
2. Detection of antidrug antibodies against human therapeutic antibodies lacking Fc-effector functions by usage of soluble Fc gamma receptor I [J] . Wessels Uwe, Poehler Alexander, Moheysen-Zadeh Miriam, Bioanalysis . 2016,第20期

机译：通过使用可溶性Fcγ受体I检测针对缺乏Fc效应子功能的人类治疗性抗体的抗药物抗体
3. Therapeutic monoclonal antibody N-glycosylation Structure, function and therapeutic potential [J] . Cymer Florian, Beck Hermann, Rohde Adelheid, Biologicals: Journal of the International Association of Biological Standardization . 2018,第期

机译：治疗性单克隆抗体N-糖基化结构，功能和治疗潜力
4. Novel Dynamic Model to Predict the Glycosylation Pattern of Monoclonal Antibodies from Extracellular Cell Culture Conditions [C] . Ohadi Kaveh, Aghamohseni Hengameh, Gadke Johannes, IFAC Symposium on Computer Applications in Biotechnology . 2014

机译：新型动态模型预测细胞外细胞培养条件中单克隆抗体的糖基化模式
5. Identification of a major subset of murine NK cells: Generation of a monoclonal antibody detecting the LGL-1 antigen and functional properties of LGL-1(+) and LGL-1(-) NK cells. [D] . Mason, Llewellyn Hoffman. 1992

机译：鉴定鼠类NK细胞的主要子集：产生检测LGL-1抗原和LGL-1（+）和LGL-1（-）NK细胞功能特性的单克隆抗体。
6. Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function [O] . Amy W. Chung, Max Crispin, Laura Pritchard, -1

机译：鉴定预测单克隆抗体Fc效应子功能的抗体糖基化结构
7. N-glycosylation heterogeneity and the influence on structure, function and pharmacokinetics of monoclonal antibodies and Fc fusion proteins [O] . Higel Fabian, Seidl Andreas, Sörgel Fritz, 2016

机译：N-糖基化异质性及其对单克隆抗体和Fc融合蛋白的结构，功能和药代动力学的影响
8. Mouse Monoclonal Antibody Specific for an Allotypic Determinant of the Igh(a) Allele of Murine IgM: Genetic and Functional Analysis of Igh-6a Epitopes Using Anti-IgM Monoclonal Antibodies. [R] . Sieckmann, D. G., Stall, A. M., Subbarao, B. 1991

机译：小鼠单克隆抗体特异性针对Igh（a）小鼠Igm等位基因的同种型决定因素：使用抗Igm单克隆抗体的Igh-6a表位的遗传和功能分析。

Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function

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