Novel synthesis of highly functionalized cyclopentane derivatives via [3+2] cycloaddition reactions of donor-acceptor cyclopropanes and (E)-3-aryl-2-cyanoacrylates

摘要

An efficient [3 + 2] cycloaddition reaction of cyanocyclopropanecarbonates and (E)-3-aryl-2-cyanoacrylates mediated by 1,8-diazabicyclo[5.4.0]undec-7-ene for the synthesis of highly functionalized cyclopentane derivatives in moderate to good yields (79%-87%) was developed. The structures of two typical products were confirmed by X-ray crystallography.