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Comparative study of strategies to prevent esophageal and periesophageal injury during atrial fibrillation ablation

机译:在心房颤动消融期间预防食管和卵泡损伤的策略比较研究

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Abstract Objective To compare the prevalence of esophageal and periesophageal thermal injury in patients undergoing radiofrequency (RF) atrial fibrillation (AF) ablation using 8?mm tip catheters during three different esophageal protection strategies. Methods Forty‐five consecutive patients with paroxysmal or persistent AF underwent first ablation procedure, besides esophagogastroduodenoscopy (EGD) combined with radial endosonography (EUS) performed before and after the pulmonary vein (PV) isolation. Before the procedure, patients were randomly assigned to one of three esophageal lesion protection strategies: group I—without any protective or monitoring dispositive and limiting RF applications to 30?W for 20?seconds, in left atrium posterior wall (LAPW); group II—power and time of RF delivery, up to 50?W for 20?seconds at LAPW, limited by esophageal temperature monitoring; group III—applications of RF in LAPW with fixed power application of 50?W for 20?seconds during continuous esophageal cooling. Results Baseline characteristics of patients were similar in all groups. The four PVs were isolated in 14 (93.3%), 13 (86.7%), and 15 (100%) patients, respectively in groups I, II, and III. The mean RF power was significantly higher ( P ??.001) in the posterior side of PVs in group III. Post‐AF ablation EGD and EUS revealed two esophageal wall ulcerations and two periesophageal mediastinal edemas only in the esophageal cooling group ( P ?=?.008). Conclusion Esophageal cooling balloon strategy resulted in a higher RF power energy delivery when ablating at the LA posterior wall, using 8?mm nonirrigated tip catheters under temperature mode control. Despite that, patients presented a relatively low incidence of esophageal and periesophaeal injuries.
机译:摘要目的比较在三种不同食管保护策略中使用8·mm尖端导管进行射频(RF)心房颤动(AF)消融患者的食管和白炽热损伤的患病率。方法对阵发性或持久性AF的连续45例患者进行了第一消融程序,除了食噬杆菌(EGD)与肺静脉(PV)分离之前和之后进行的径向内皮内剖视(EUS)。在该程序之前,患者被随机分配给三种食管病变保护策略之一:I-I - 没有任何保护或监测分数,并将RF应用限制在30?W左右,在左心房(LAPW)中。第II族电源和RF递送的时间,最高可达50?W,在LAPW时秒为20?秒,受食管温度监测的限制; LAPW中RF的III族应用,固定功率施加为50μm2.连续食管冷却期间20秒钟。结果患者的基线特征在所有群体中相似。在I,II和III组中分别分别分别为14(93.3%),13(86.7%)和15名(100%)患者中分离了四种PV。在III族PV的PVS的后侧,平均RF功率显着升高(p≤≤001)。后AF消融EGD和EUS仅揭示了两种食管壁溃疡和两种食管纵隔水肿,仅在食道冷却基团(P?= 008)。结论食管冷却球囊策略导致在LA后壁烧蚀时较高的RF功率输送,在温度模式控制下使用8Ωmm非静脉尖端导管。尽管如此,患者呈现出相对较低的食管和过渗塑损伤的发生率。

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