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Surgical repair of aortic coarctation in pediatric age: A single center two decades experience

机译:儿科时代主动脉造成的手术修复:单中心二十年的经验

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Abstract Background To evaluate early and long‐term results of surgical treatment of aortic coarctation (CoAo) in infants and children. Methods A retrospective clinical review of patients less than 18 years with CoAo, undergoing surgery between 1995 and 2015. Data were retrieved from our institutional database, to identify preoperative and postoperative characteristics. Statistical analysis was performed by bivariate, Cox's, and logistic regression analysis. Results Three hundred forty‐one consecutive patients (male/female: 192/149; the median age at surgery of 25 days; interquartile range [IQR], 10‐143?days) were included; 187 patients were less than 1 month (54.9%); 276 underwent extended end‐to‐end anastomosis (EEEA) (80.9%). Hypoplastic aortic arch (HAA) occurred in 34.6% and bicuspid aortic valve in 21.1%. The isolated type was present in 249 (73.0%). Significant postoperative complications occurred in 5.6%. Thirty‐day mortality was 1.4%. At a median follow‐up of 10.2 years (IQR, 6‐15?years; FU completeness, 91.2%), there were eight late deaths (2.6%), most in the complex type. Among 298 survivors, 284 (95.3%) were in NYHA class I; 10 (3.0%) were on antihypertensive treatment. Reinterventions on aortic arch occurred only in 4.5%, being HAA a significant risk factor for reoperation ( P ?=?0.00173). Freedom from mortality and reintervention on aorta at 21 years were 93.5% and 93.6%, respectively. Conclusions Surgical repair of CoAo by EEEA without CPBP is a safe and low‐risk procedure, concerning either early or late outcomes, despite the presence of HAA and neonatal age can influence recoarctation. Most patients are clinically well in the long‐term, and only a few require antihypertensive therapy.
机译:评估婴幼儿主动脉造币(Coao)手术治疗的早期和长期结果的抽象背景。方法对1995年至二零一五年之间的手术较少超过18年的患者的回顾性临床审查。从我们的机构数据库中检索数据,以识别术前和术后特征。通过双变量,Cox和Logistic回归分析进行统计分析。结果三百四十一次连续患者(男性/女:192/149;手术中位年龄为25天;局部脚步范围[IQR],10-143日); 187名患者少于1个月(54.9%); 276经历了延长的端到端吻合术(EEEA)(80.9%)。 Hypoplastic主动脉弓(HAA)发生在34.6%和双囊主动脉瓣膜21.1%中。分离的类型在249中存在(73.0%)。显着的术后并发症发生在5.6%。三十天的死亡率为1.4%。在10.2岁的中位出现(IQR,6-15岁以下);福完整性,91.2%),有八个后期死亡(2.6%),大多数是复杂的类型。在298个幸存者中,在NYHA级别I级(95.3%); 10(3.0%)是对抗高血压治疗。对主动脉弓的重新纳入仅在4.5%中发生,是HAA重新进食的显着风险因素(P?= 0.00173)。从21岁处自由地从死亡率和重新营养到主动脉的自由度分别为93.5%和93.6%。结论在没有CPBP的情况下,eeea的Coao手术修复是一种安全和低风险的程序,关于早期或晚期结果,尽管存在Haa和新生儿年龄可以影响重新来源。大多数患者在长期临床上很好地良好,只需要少量抗高血压治疗。

著录项

  • 来源
    《Journal of cardiac surgery.》 |2019年第5期|共10页
  • 作者单位

    Department of Cardiac Thoracic and Vascular SciencesSection of Pediatric and Congenital Cardiac;

    Department of Statistical SciencesUniversity of PaduaPadua Italy;

    Department of Woman and Child's HealthSection of Pediatric Cardiology Medical School University;

    Department of Cardiac Thoracic and Vascular SciencesSection of Pediatric and Congenital Cardiac;

    Department of Cardiac Thoracic and Vascular SciencesSection of Pediatric and Congenital Cardiac;

    Department of Cardiac Thoracic and Vascular SciencesSection of Pediatric and Congenital Cardiac;

    Department of Cardiac Thoracic and Vascular SciencesSection of Pediatric and Congenital Cardiac;

    Department of Cardiac Thoracic and Vascular SciencesSection of Pediatric and Congenital Cardiac;

    Department of Woman and Child's HealthSection of Pediatric Cardiology Medical School University;

    Department of Cardiac Thoracic and Vascular SciencesSection of Pediatric and Congenital Cardiac;

    Department of Cardiac Thoracic and Vascular SciencesSection of Pediatric and Congenital Cardiac;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 心脏血管和淋巴系外科学;
  • 关键词

    aorta and great vessels; clinical review; congenital heart disease;

    机译:主动脉和伟大的船只;临床评论;先天性心脏病;

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