Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-beta Concentrations and Cognition Outcomes in Alzheimer's Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial

Boada Merce; Anaya Fernando; Ortiz Pilar; Olazaran Javier; Shua-Haim Joshua R.; Obisesan Thomas O.; Hernandez Isabel; Munoz Joan; Buendia Mar; Alegret Montserrat; Lafuente Asuncion; Tarraga Lluis; Nunez Laura; Torres Mireia; Grifols Joan Ramon; Ferrer Isidre; Lopez Oscar L.; Paez Antonio

首页> 外文期刊>Journal of Alzheimer's disease: JAD >Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-beta Concentrations and Cognition Outcomes in Alzheimer's Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial

【24h】

Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-beta Concentrations and Cognition Outcomes in Alzheimer's Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial

机译：血浆交换对5％白蛋白的疗效和安全性，以改变阿尔茨海默病患者的脑脊液和血浆淀粉样蛋白β浓度和认知结果：多中心，随机，受控临床试验

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Background: Studies conducted in animal models and humans suggest the presence of a dynamic equilibrium of amyloid-beta (A beta) peptide between cerebrospinal fluid (CSF) and plasma compartments.

机译：背景：在动物模型和人体中进行的研究表明脑脊液（CSF）和等离子体隔室之间的淀粉样蛋白β（β）肽的动态平衡存在。

著录项

来源
《Journal of Alzheimer's disease: JAD》 |2017年第1期|共15页
作者
Boada Merce; Anaya Fernando; Ortiz Pilar; Olazaran Javier; Shua-Haim Joshua R.; Obisesan Thomas O.; Hernandez Isabel; Munoz Joan; Buendia Mar; Alegret Montserrat; Lafuente Asuncion; Tarraga Lluis; Nunez Laura; Torres Mireia; Grifols Joan Ramon; Ferrer Isidre; Lopez Oscar L.; Paez Antonio;
展开▼
作者单位

Inst Catala Neurociencies Aplicades Memory Clin Gran Via Carles III 85 Bis Barcelona 08028 Spain;

Hosp Gen Univ Vall Hebron Neurol Serv Barcelona Spain;

Banc Sang &

Teixits Barcelona Spain;

Hosp Gen Univ Vall Hebron Neurol Serv Barcelona Spain;

Alzheimers Res Corp Mid Atlantic Geriatr Assoc Manchester NJ USA;

Howard Univ Dept Internal Med Washington DC 20059 USA;

Inst Catala Neurociencies Aplicades Memory Clin Gran Via Carles III 85 Bis Barcelona 08028 Spain;

Banc Sang &

Teixits Barcelona Spain;

Inst Catala Neurociencies Aplicades Memory Clin Gran Via Carles III 85 Bis Barcelona 08028 Spain;

Inst Catala Neurociencies Aplicades Memory Clin Gran Via Carles III 85 Bis Barcelona 08028 Spain;

Inst Catala Neurociencies Aplicades Memory Clin Gran Via Carles III 85 Bis Barcelona 08028 Spain;

Inst Catala Neurociencies Aplicades Memory Clin Gran Via Carles III 85 Bis Barcelona 08028 Spain;

Inst Grifols SA Clin Trials Dept Barcelona Spain;

Inst Grifols SA Clin Trials Dept Barcelona Spain;

Banc Sang &

Teixits Barcelona Spain;

Hosp Univ Bellvitge Inst Neuropatol Barcelona Spain;

Univ Pittsburgh Sch Med Dept Neurol Pittsburgh PA 15261 USA;

Inst Grifols SA Clin Trials Dept Barcelona Spain;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
关键词
Albumin; Alzheimer's disease; CSF A beta; plasma A beta; plasma exchange;

机译：白蛋白;阿尔茨海默病;CSFAβ;血浆β;等离子交换;

相似文献

外文文献
中文文献
专利

1. Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-beta Concentrations and Cognition Outcomes in Alzheimer's Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial [J] . Boada Merce, Anaya Fernando, Ortiz Pilar, Journal of Alzheimer's disease: JAD . 2017,第1期

机译：血浆交换对5％白蛋白的疗效和安全性，以改变阿尔茨海默病患者的脑脊液和血浆淀粉样蛋白β浓度和认知结果：多中心，随机，受控临床试验
2. Efficacy and Blood Plasmalogen Changes by Oral Administration of Plasmalogen in Patients with Mild Alzheimer's Disease and Mild Cognitive Impairment: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial [J] . Takehiko Fujino, Tatsuo Yamada, Takashi Asada, EBioMedicine . 2017,第4期

机译：轻度阿尔茨海默氏病和轻度认知障碍患者口服血浆生成素的疗效和血液中血浆血浆生成素的变化：多中心，随机，双盲，安慰剂对照试验
3. Efficacy and safety of GV1001 in patients with moderate-to-severe Alzheimer’s disease already receiving donepezil: a phase 2 randomized, double-blind, placebo-controlled, multicenter clinical trial [J] . Seong-Ho Koh, Hyuk Sung Kwon, Seong Hye Choi, Alzheimer s Research & Therapy . 2021,第1期

机译：GV1001在中度至重度的阿尔茨海默病患者中的疗效和安全性已经接受过奈哌齐：A相随机，双盲，安慰剂控制，多中心临床试验
4. CEREBROSPINAL FLUID AND PLASMA OF ALZHEIMER PATIENTS PROMOTE 5-AMYLOID FIBRIL FORMATION IN VITRO [C] . K. Ono, M Noguchi-Shinohara, M Samuraki, International Symposium on Amyloidosis . 2008

机译：阿尔茨海默患者脑脊液和血浆促进 5-淀粉样蛋白原纤维形成体外
5. Cerebrospinal fluid diversion and intrathecal pressure monitoring in the setting of acute spinal cord injury: A multicenter prospective randomized control trial. [D] . Anthony, Michael P. 2013

机译：急性脊髓损伤情况下的脑脊液转移和鞘内压监测：一项多中心前瞻性随机对照试验。
6. Efficacy and Safety of Plasma Exchange with 5 Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer’s Disease Patients: A Multicenter Randomized Controlled Clinical Trial [O] . Mercè Boada, Fernando Anaya, Pilar Ortiz, -1

机译：用5％白蛋白进行血浆交换以改善脑脊髓液和血浆淀粉样β-β浓度和认知结局在阿尔茨海默氏病患者中的功效和安全性：一项多中心随机对照临床试验
7. Efficacy and Blood Plasmalogen Changes by Oral Administration of Plasmalogen in Patients with Mild Alzheimer's Disease and Mild Cognitive Impairment: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial [O] . Takehiko Fujino, Tatsuo Yamada, Takashi Asada, 2017

机译：口服施用缩醛磷脂治疗轻度阿尔茨海默病和轻度认知障碍患者的疗效和血浆原胶原变化：多中心，随机，双盲，安慰剂对照试验
8. Multicenter, Randomized Controlled Trial of Cerebrospinal Fluid Drainage in Acute Spinal Cord Injury. [R] . Theodore, N., Kopjar, V. 2017

机译：急性脊髓损伤脑脊液引流的多中心随机对照试验。

Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-beta Concentrations and Cognition Outcomes in Alzheimer's Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial

摘要

著录项

相似文献

相关主题

期刊订阅