Global dynamics of delayed CHIKV infectionmodel with multitarget cells

摘要

We propose a latent chikungunya viral infection model with multitarget cells and saturated incidence rate. The model is an (3n + 2)-dimensional system of nonlinear delay differential equations (DDEs) that describes the population dynamics ofCHIKV, n categories of uninfected target cells, n categories of infected cells and antibodies. The model is incorporated by intracellular discrete or distributed time delays. The qualitative behavior of the model is studied. We investigate the global stability of the equilibria of the models by using direct Lyapunov method. The effect of the time delay on the stability of the equilibria has also been illustrated by numerical simulations.