Local functional connectivity density is closely associated with the response of electroconvulsive therapy in major depressive disorder

摘要

Electroconvulsive therapy (ECT) has been widely used for treatment of neuropsychiatric disorders including schizophrenia and depression (Kellner et al., 2012; Lisanby, 2007; Tharyan and Adams, 2005). Compared to other types of treatment, ECT is the optimal choice for therapy of major depressive disorder (MDD), especially for treatmentresistant depressive disorder,given itsrapid action (Kellneretal.,2012; Lisanby, 2007).