Hodgkin Lymphoma at the Paediatric Oncology Unit of Gabriel-Toure Teaching Hospital Bamako (Mali): 3 years experience

摘要

Abstract Introduction: Approximately 20 000 new cases of Hodgkin lymphoma are diagnosed each year in North America and Europe. However in Africa, the incidence of this condition is almost unknown. While publications from western countries and the rest of world are numerous in the literature, few data from Africa about this malignancy are available. The aim of this retro and prospective, unicentric study over 3 years is to describe the epidemiologic, pathologic, clinical and therapeutic aspects of children treated for Hodgkin lymphoma in our paediatric oncology unit of Gabriel-Toure Hospital, Bamako (Mali).Patients and methods: From January 2005 to December 2007, all children under 18 years of age, with histologically proven Hodgkin lymphoma, not previously treated by chemotherapy and HIV negative, were included in this study. Informed consent was obtained from parents. The treatment protocol was the GFAOP (Groupe franco-africain d'oncologie pediatrique) Hodgkin lymphoma treatment protocol: COPP/ABV (Cyclophosphamid, Vincristin, Prednisone, Procarbazin, Adriamycine, bleomycin and vinblastine). Results: During the study period, 217 cancer cases were diagnosed in our centre. Of these cases, 7 were Hodgkin Lymphoma (0.04%). The average age was 11.7 years.