Percutaneous Left Atrial Appendage Closure With the LAmbre Device for Stroke Prevention in Atrial Fibrillation A Prospective, Multicenter Clinical Study

摘要

OBJECTIVES The authors sought to assess the clinical outcomes of left atrial appendage (LAA) closure with the LAmbre closure system in patients with nonvalvular atrial fibrillation (NVAF).& para;& para;BACKGROUND Over 90% of thrombi are located in the LAA in NVAF patients.& para;& para;METHODS A prospective, multicenter study was conducted in 153 NVAF patients with CHADS(2) score >= 1.& para;& para;RESULTS The LAA was successfully occluded in 152 patients. Serious complications occurred in 5 patients. During the 12-month follow-up, ischemic stroke occurred in 2 patients, 1 patient had incomplete LAA sealing, and there was no device embolization.& para;& para;CONCLUSIONS LAA closure with the LAmbre device shows encouraging results for stroke prevention. (C) 2017 Published by Elsevier on behalf of the American College of Cardiology Foundation.