Induction of immunogenic tumor cell death by a novel immune-oncolytic Vaccinia virus strain leads to robust antitumor immune responses directed against neo-epitopes

Rojas J. J.; Riederer S.; Van Hoecke L.; Saelens X.; Lehmann M. H.; Sutter G.

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Induction of immunogenic tumor cell death by a novel immune-oncolytic Vaccinia virus strain leads to robust antitumor immune responses directed against neo-epitopes

机译：一种新型免疫溶血病毒株的免疫原性肿瘤细胞死亡诱导导致针对新表位的鲁棒抗肿瘤免疫应答

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来源
《Human gene therapy》 |2019年第11期|共2页
作者
Rojas J. J.; Riederer S.; Van Hoecke L.; Saelens X.; Lehmann M. H.; Sutter G.;
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作者单位

Ludwig Maximilians Univ Munchen Munich Germany;

Ludwig Maximilians Univ Munchen Munich Germany;

VIB Ctr Med Biotechnol Ghent Belgium;

VIB Ctr Med Biotechnol Ghent Belgium;

Ludwig Maximilians Univ Munchen Munich Germany;

Ludwig Maximilians Univ Munchen Munich Germany;

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原文格式 PDF
正文语种 eng
中图分类治疗学;
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专利

1. Induction of immunogenic tumor cell death by a novel immune-oncolytic Vaccinia virus strain leads to robust antitumor immune responses directed against neo-epitopes [J] . Rojas J. J., Riederer S., Van Hoecke L., Human gene therapy . 2019,第11期

机译：一种新型免疫溶血病毒株的免疫原性肿瘤细胞死亡诱导导致针对新表位的鲁棒抗肿瘤免疫应答
2. The intrinsic immunogenic properties of cancer cell lines, immunogenic cell death, and how these influence host antitumor immune responses [J] . Aaes Tania Love, Vandenabeele Peter Cell death and differentiation . 2021,第3期

机译：癌细胞系，免疫原性细胞死亡的内在免疫原性以及这些影响宿主抗肿瘤免疫应答
3. Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity [J] . Mari Hirvinen, Cristian Capasso, Kilian Guse, Molecular Therapy - Oncolytics . 2016,第11期

机译：溶瘤痘苗病毒表达DAI可增强病毒的免疫原性并增强抗肿瘤免疫力
4. Vectorization in an Oncolytic Vaccinia Virus of Antibodies Against Programmed Cell Death -1 (PD-1) Allows Their Intratumoral Delivery and an Improved Tumor-Growth Inhibition [C] . Jean-Baptiste March, Patricia Kleinpeter, Laetitia Fend, Protein Engineering Summit. . 2018

机译：矢量化在抗体抗体的抗体疫苗病毒中，针对编程的细胞死亡-1（PD-1）允许其肿瘤内递送和改善的肿瘤生长抑制
5. Applicability of vaccinia virus as cloning and expression vector for bacterial genes: Mice immune responses to vaccinia virus expressing Brucella abortus and Listeria monocytogenes antigens. [D] . Baloglu, Simge. 2006

机译：牛痘病毒作为细菌基因的克隆和表达载体的适用性：小鼠对表达布鲁氏菌流产单核细胞增生李斯特菌抗原的牛痘病毒的免疫反应。
6. Repeated intratumoral administration of ONCOS-102 leads to systemic antitumor CD8+ T-cell response and robust cellular and transcriptional immune activation at tumor site in a patient with ovarian cancer [O] . L Vassilev, T Ranki, T Joensuu, 2015

机译：重复肿瘤内给药ONCOS-102可导致系统性抗肿瘤CD8 + T细胞反应以及卵巢癌患者肿瘤部位的强大细胞和转录免疫活化
7. Repeated intratumoral administration of ONCOS-102 leads to systemic antitumor CD8+T-cell response and robust cellular and transcriptional immune activation at tumor site in a patient with ovarian cancer [O] . L Vassilev, T Ranki, T Joensuu, 2015

机译：重复的肿瘤-102的肿瘤内施用导致卵巢癌患者肿瘤部位的全身抗肿瘤CD8 + T细胞响应和鲁棒细胞和转录免疫激活

Induction of immunogenic tumor cell death by a novel immune-oncolytic Vaccinia virus strain leads to robust antitumor immune responses directed against neo-epitopes

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