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No relationship between late HIV HIV diagnosis and social deprivation in newly diagnosed patients in France

机译:在法国新诊断患者的艾滋病毒艾滋病毒诊断与社会剥夺之间没有关系

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Objectives The aim of the study was to determine whether there is a relationship between social deprivation and time of HIV diagnosis in France. Methods Prospectively collected data from a multicentre database were used in the study. Patients with a first HIV diagnosis between 1 January 2014 and 31 December 2015 were selected from the database. Deprivation was measured using the European Deprivation Index ( EDI ), which is an ecological index constructed from the address of residence and based on the smallest geographical census unit, in which individuals are classified so as to be comparable with national quintiles. Time of diagnosis was classified as being at an early, intermediate, late, or advanced stage of disease. Age, gender, distance from home to HIV centre, most probable route of infection, and hepatitis B or C coinfection were considered in the analysis. Because of a strong interaction between gender and most probable route of infection, we constructed a ‘population’ variable: men who have sex with men ( MSM ), heterosexual men and women. Results Of 1421 newly diagnosed patients, 44% were diagnosed either late or at an advanced stage of disease, and 46.3% were in the highest deprivation quintile. Using multivariate logistic regression, ‘population’ [odds ratio ( OR ) 0.62 (95% confidence interval ( CI ) 0.48–0.78) for MSM compared with women] and age [ OR 1.39 (95% CI 1.07–1.80), 1.72 (1.32–2.23) and 1.86 (1.40–2.47) for the second, third and fourth quartiles, respectively, compared with the first quartile] were found to be related to late diagnosis. EDI level was not related to late HIV diagnosis. Conclusions ‘Population’ seems to be more relevant than EDI to define evidence‐based interventions to limit late diagnosis.
机译:目标该研究的目的是确定法国艾滋病毒诊断时的社会剥夺与时间之间是否存在关系。方法在研究中使用了来自Multicentre数据库的预期收集数据。 2014年1月1日至2015年12月31日至2015年12月31日之间的第一次艾滋病病毒诊断的患者被选中。使用欧洲剥夺指数(EDI)测量剥夺,该指数是从住宅地址构建的生态指数,并基于最小的地理人口普查单位,其中个体被分类为与国家昆泰相媲美。诊断时间被归类为早期,中级,晚期或晚期疾病阶段。在分析中考虑了年龄,性别,离家,距离HIV中心的距离,最有可能的感染途径和乙型肝炎或C杂环。由于性别和最可能的感染途径之间存在强烈的互动,我们构建了一个“人口”变量:与男人(MSM),异性恋男女发生性行为的男性。结果1421年新诊断的患者,44%被诊断为晚期或处于晚期疾病,46.3%是最高剥夺五分子。使用多变量逻辑回归,“人口”[odds比率(或)0.62(CI)与女性的MSM为0.62(95%)0.48-0.78),年龄[或1.39(95%CI 1.07-1.80),1.72(1.32与第一个四分位数相比,第二,第三和第四个四分位数分别与晚期诊断有关,分别为-2.23)和1.86(1.40-2.47)。 EDI水平与晚期艾滋病毒诊断无关。结论“人口”似乎比EDI更加重要,以确定基于证据的干预措施来限制迟到的诊断。

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