An MRS Phantom Design with Multiple Compartments for Mimicking IDH Mutant and IDH Wild-Type Brain Tumors

摘要

MR spectroscopy (MRS) sequences are first validated on phantoms before in vivo studies. Previous studies employed 3D printers to produce MR phantoms for other MRI modalities or generic use~(1,2). In this study, we designed and 3D printed a human head sized multi-compartment MRS phantom, which includes a compartment with solution mimicking an isocitrate dehydrogenase wild-type (IDH-wt) glioma, and another compartment with solution mimicking an IDH mutant (IDH-mut) glioma.