Human endometrial epithelial telomerase is important for epithelial proliferation and glandular formation with potential implications in endometriosis

Valentijn A. J.; Saretzki G.; Tempest N.; Critchley H. O. D.; Hapangama D. K.

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Human endometrial epithelial telomerase is important for epithelial proliferation and glandular formation with potential implications in endometriosis

机译：人子宫内膜上皮端粒酶对上皮性增殖和腺体形成是重要的，具有内膜异位症的潜在影响

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STUDY QUESTION: How does regulation of telomerase activity (TA) in human endometrial epithelial cells (EEC) by ovarian hormones impact on telomere lengths (TL) and cell proliferation?

机译：研究问题：通过卵巢激素对端粒长度（T1）和细胞增殖的影响如何调节人类子宫内膜上皮细胞（EEC）的调节？

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来源
《Human Reproduction》 |2015年第12期|共13页
作者
Valentijn A. J.; Saretzki G.; Tempest N.; Critchley H. O. D.; Hapangama D. K.;
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作者单位

Univ Liverpool Inst Translat Med Dept Womens &

Childrens Hlth Liverpool L8 7SS Merseyside;

Newcastle Univ Inst Cell &

Mol Biosci Newcastle Upon Tyne NE4 5PL Tyne &

Wear England;

Univ Liverpool Inst Translat Med Dept Womens &

Childrens Hlth Liverpool L8 7SS Merseyside;

Univ Edinburgh MRC Ctr Reprod Hlth Edinburgh EH16 4TJ Midlothian Scotland;

Univ Liverpool Inst Translat Med Dept Womens &

Childrens Hlth Liverpool L8 7SS Merseyside;

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原文格式 PDF
正文语种 eng
中图分类人体生理学;
关键词
endometrium; telomere length; telomerase; progesterone; Imetelstat; endometriosis; endometrial epithelium; proliferation; cell culture; 3D culture;

机译：子宫内膜;端粒长度;端粒酶;孕酮;IMETELSTAT;子宫内膜异位症;子宫内膜上皮;增殖;细胞培养;3D文化;3D文化;

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专利

1. Human endometrial epithelial telomerase is important for epithelial proliferation and glandular formation with potential implications in endometriosis [J] . Valentijn A. J., Saretzki G., Tempest N., Human Reproduction . 2015,第12期

机译：人子宫内膜上皮端粒酶对上皮性增殖和腺体形成是重要的，具有内膜异位症的潜在影响
2. MicroRNA‐488 inhibits endometrial glandular epithelial cell proliferation, migration, and invasion in endometriosis mice via Wnt by inhibiting FZD7 [J] . Hui Zhu, Xi‐Xia Cao, Juan Liu, Journal of cellular and molecular medicine. . 2019,第4期

机译：MicroRNA‐488通过抑制FZD7抑制Wnt通过Wnt抑制子宫内膜异位症小鼠子宫内膜腺上皮细胞的增殖，迁移和侵袭
3. Effects of matrix stiffness on epithelial to mesenchymal transition-like processes of endometrial epithelial cells: Implications for the pathogenesis of endometriosis [J] . Sachiko Matsuzaki, Claude Darcha, Jean-Luc Pouly, Scientific reports. . 2017,第1期

机译：基质刚度对子宫内膜细胞结石转型过程的基质刚度：对子宫内膜异位症发病机制的影响
4. Heavy ion induced transformation of telomerase immortalized human small airway epithelial cells [C] . Chang Q. Piao, Yong L. Zhao, M. Suzuki, International Conference on High Levels of Natural Radiation and Radon Areas . 2005

机译：重离离子诱导端粒酶转化永生化人类小气道上皮细胞
5. Antigen trafficking within Chlamydia trachomatis-infected polarized human endometrial epithelial cells. [D] . Giles, David K. 2008

机译：沙眼衣原体感染的极化人子宫内膜上皮细胞内的抗原运输。
6. MicroRNA‐488 inhibits endometrial glandular epithelial cell proliferation migration and invasion in endometriosis mice via Wnt by inhibiting FZD7 [O] . Hui Zhu, Xi‐Xia Cao, Juan Liu, 2019

机译：MicroRNA‐488通过抑制FZD7抑制Wnt通过Wnt抑制子宫内膜异位症小鼠子宫内膜腺上皮细胞的增殖迁移和侵袭
7. Human endometrial epithelial telomerase is important for epithelial proliferation and glandular formation with potential implications in endometriosis [O] . A.J. Valentijn, G. Saretzki, N. Tempest, 2015

机译：人子宫内膜上皮端粒酶对于上皮性增殖和腺体形成是具有潜在内膜异位症的潜在影响的重要性

Human endometrial epithelial telomerase is important for epithelial proliferation and glandular formation with potential implications in endometriosis

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