Testicular germ cell tumors: revisiting a series in light of the new WHO classification and AJCC staging systems, focusing on challenges for pathologists

Jo?o Lobo; Ana Laura Costa; Bárbara Vilela-Salgueiro; ?ngelo Rodrigues; Rita Guimar?es; Mariana Cantante; Paula Lopes; Luís Antunes; Carmen Jerónimo; Rui Henrique

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Testicular germ cell tumors: revisiting a series in light of the new WHO classification and AJCC staging systems, focusing on challenges for pathologists

机译：睾丸生殖细胞肿瘤：根据新的全新分类和AJCC分期系统重新审视系列，重点关注病理学家的挑战

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50%EC component, but not rete testis invasion, were associated with higher stage (P?

机译：50％的EC组分，但没有Rete Testis侵袭，与较高阶段相关（P？<〜001，P？= 009）。关于SES，肿瘤大小和阶段之间存在关联（p？= 004）和LVI（p？<= 001）。在雇用AJCC第8版时，只有四名患者披露了阶段组。疾病复发/进展发生在5.4％的病例中。在两种情况下，初级TGCT中不存在转移术中的肿瘤成分。 5岁的整体生存率为98.6％。 TGCTS是挑战的肿瘤，病理学家和临床医生必须了解最近的分类和分期更新，以获得充分定制治疗策略。

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来源
《Human Pathology》 |2018年第2018期|共12页
作者
Jo?o Lobo; Ana Laura Costa; Bárbara Vilela-Salgueiro; ?ngelo Rodrigues; Rita Guimar?es; Mariana Cantante; Paula Lopes; Luís Antunes; Carmen Jerónimo; Rui Henrique;
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作者单位

Department of Pathology Portuguese Oncology Institute of Porto (IPOP);

Cancer Biology and Epigenetics Group Research Center of Portuguese Oncology Institute of Porto;

Cancer Biology and Epigenetics Group Research Center of Portuguese Oncology Institute of Porto;

Department of Pathology Portuguese Oncology Institute of Porto (IPOP);

Department of Pathology Portuguese Oncology Institute of Porto (IPOP);

Department of Pathology Portuguese Oncology Institute of Porto (IPOP);

Department of Pathology Portuguese Oncology Institute of Porto (IPOP);

Department of Epidemiology Portuguese Oncology Institute of Porto (IPOP);

Cancer Biology and Epigenetics Group Research Center of Portuguese Oncology Institute of Porto;

Department of Pathology Portuguese Oncology Institute of Porto (IPOP);

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原文格式 PDF
正文语种 eng
中图分类病理学;
关键词
Testicular cancer; Germ cell tumors; Histopathology; Prognosis; AJCC; WHO;

机译：睾丸癌;生殖细胞肿瘤;组织病理学;预后;AJCC;谁;

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专利

1. Testicular germ cell tumors: revisiting a series in light of the new WHO classification and AJCC staging systems, focusing on challenges for pathologists [J] . Jo?o Lobo, Ana Laura Costa, Bárbara Vilela-Salgueiro, Human Pathology . 2018,第期

机译：睾丸生殖细胞肿瘤：根据新的全新分类和AJCC分期系统重新审视系列，重点关注病理学家的挑战
2. The challenges of diagnosing testicular germ-cell tumours: revisiting a series of 166 tumours in light of the new WHO classification and AJCC staging system [J] . Lobo J., Costa A. L., Vilela-Salgueiro B., Virchows Archiv: an international journal of pathology . 2018,第Suppla1期

机译：诊断睾丸生殖细胞肿瘤的挑战：根据新的全新分类和AJCC分期系统重新探测一系列166个肿瘤
3. The challenges of diagnosing testicular germ-cell tumours: revisiting a series of 166 tumours in light of the new WHO classification and AJCC staging system [J] . Lobo J., Costa A. L., Vilela-Salgueiro B., Virchows Archiv: an international journal of pathology . 2018,第Suppla1期

机译：诊断睾丸生殖细胞肿瘤的挑战：根据新的全新分类和AJCC分期系统重新探测一系列166个肿瘤
4. Expression Failure of the p63 and Notch Signaling Systems is Associated with the Pathogenesis of Testicular Germ Cell Tumor [C] . T. Hayashi, S. Yoshida, A. Yoshinaga, International Congress of Andrology . 2005

机译：P63和Notch信号传导系统的表达失败与睾丸生殖细胞肿瘤的发病机制有关
5. A novel mouse model to elucidate the origins and therapeutic sensitivity of testicular germ cell tumors [D] . Pierpont, Timothy M. 2017

机译：新型小鼠模型，阐明睾丸生殖细胞肿瘤的起源和治疗敏感性
6. Age-Dependent Presentation and Clinical Course of 1465 Patients Aged 0 to Less than 18 Years with Ovarian or Testicular Germ Cell Tumors; Data of the MAKEI 96 Protocol Revisited in the Light of Prenatal Germ Cell Biology [O] . Gabriele Calaminus, Dominik T. Schneider, Dietrich von Schweinitz, 2020

机译：1465名0岁至小于18岁的卵巢或睾丸生殖细胞肿瘤患者的年龄依赖性表现和临床过程； MAKEI 96协议的数据根据产前生殖细胞生物学进行了重新探讨
7. Performance Characteristics of Clinical Staging Modalities for Early Stage Testicular Germ Cell Tumors: A Systematic Review [O] . Phillip M. Pierorazio, Joseph G. Cheaib, Giorgia Tema, 2020

机译：早期睾丸生殖细胞肿瘤临床分期型号的性能特征：系统综述

Testicular germ cell tumors: revisiting a series in light of the new WHO classification and AJCC staging systems, focusing on challenges for pathologists

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