Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis (vol 28, pg 2459, 2019)

Guerrero Erika N.; Mitra Joy; Wang Haibo; Rangaswamy Suganya; Hegde Pavana M.; Basu Priyadarshini; Rao K. S.; Hegde Muralidhar L.

首页> 外文期刊>Human Molecular Genetics >Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis (vol 28, pg 2459, 2019)

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Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis (vol 28, pg 2459, 2019)

机译：肌萎缩横向硬化相关的TDP-43突变Q331K可防止XRCC4-DNA连接酶4络合物的核转位，并与基因组损伤介导的神经元细胞凋亡相关（Vol 28，PG 2459,2019）

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来源
《Human Molecular Genetics》 |2019年第18期|共2页
作者
Guerrero Erika N.; Mitra Joy; Wang Haibo; Rangaswamy Suganya; Hegde Pavana M.; Basu Priyadarshini; Rao K. S.; Hegde Muralidhar L.;
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作者单位

Houston Methodist Res Inst Dept Radiat Oncol Houston TX 77030 USA;

Houston Methodist Res Inst Dept Radiat Oncol Houston TX 77030 USA;

Houston Methodist Res Inst Dept Radiat Oncol Houston TX 77030 USA;

Houston Methodist Res Inst Dept Radiat Oncol Houston TX 77030 USA;

Houston Methodist Res Inst Dept Radiat Oncol Houston TX 77030 USA;

Houston Methodist Res Inst Dept Radiat Oncol Houston TX 77030 USA;

Inst Invest Cient &

Serv Alta Tecnol INDICASAT AI Ctr Neurosci City Of Knowledge Panama;

Houston Methodist Res Inst Dept Radiat Oncol Houston TX 77030 USA;

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正文语种 eng
中图分类医学遗传学;
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1. Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis (vol 28, pg 2459, 2019) [J] . Guerrero Erika N., Mitra Joy, Wang Haibo, Human Molecular Genetics . 2019,第18期

机译：肌萎缩横向硬化相关的TDP-43突变Q331K可防止XRCC4-DNA连接酶4络合物的核转位，并与基因组损伤介导的神经元细胞凋亡相关（Vol 28，PG 2459,2019）
2. Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis [J] . Guerrero Erika N., Mitra Joy, Wang Haibo, Human Molecular Genetics . 2019,第15期

机译：肌营养的外侧硬化相关的TDP-43突变Q331K防止XRCC4-DNA连接酶4络合物的核转位，并与基因组损伤介导的神经元细胞凋亡相关
3. Genome aging: somatic mutation in the brain links age-related decline with disease and nominates pathogenic mechanisms (vol 28, pg R197, 2019) [J] . Lodato Michael A., Walsh Christopher A. Human Molecular Genetics . 2020,第3期

机译：Genome老化：脑中的体细胞突变与疾病的年龄相关的衰退，并提名致病机制（Vol 28，PG R197,2019）
4. Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis [O] . Erika N Guerrero, Joy Mitra, Haibo Wang, -1

机译：肌萎缩性侧索硬化症相关的TDP-43突变Q331K阻止XRCC4-DNA连接酶4复合物的核易位并与基因组损伤介导的神经元凋亡相关
5. Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis [O] . Erika N Guerrero, Joy Mitra, Haibo Wang, 2019

机译：肌营养的外侧硬化相关TDP-43突变Q331K防止XRCC4-DNA连接酶4络合物的核转位，并与基因组损伤介导的神经元细胞凋亡相关联

Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis (vol 28, pg 2459, 2019)

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