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Highlighting the evidence gap: how cost-effective are interventions to improve early childhood nutrition and development?

机译:突出证据差距:干预措施如何提高童年营养和发展的干预措施?

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摘要

There is growing evidence of the effectiveness of early childhood interventions to improve the growth and development of children. Although, historically, nutrition and stimulation interventions may have been delivered separately, they are increasingly being tested as a package of early childhood interventions that synergistically improve outcomes over the life course. However, implementation at scale is seldom possible without first considering the relative cost and cost-effectiveness of these interventions. An evidence gap in this area may deter large-scale implementation, particularly in low-and middle-income countries. We conduct a literature review to establish what is known about the cost-effectiveness of early childhood nutrition and development interventions. A set of predefined search terms and exclusion criteria standardized the search across five databases. The search identified 15 relevant articles. Of these, nine were from studies set in high-income countries and six in low-and middle-income countries. The articles either calculated the cost-effectiveness of nutritionspecific interventions (n = 8) aimed at improving child growth, or parenting interventions (stimulation) to improve early childhood development (n = 7). No articles estimated the cost-effectiveness of combined interventions. Comparing results within nutrition or stimulation interventions, or between nutrition and stimulation interventions was largely prevented by the variety of outcome measures used in these analyses. This article highlights the need for further evidence relevant to low-and middle-income countries. To facilitate comparison of cost-effectiveness between studies, and between contexts where appropriate, a move towards a common outcome measure such as the cost per disability-adjusted life years averted is advocated. Finally, given the increasing number of combined nutrition and stimulation interventions being tested, there is a significant need for evidence of cost-effectiveness for combined programmes. This too would be facilitated by the use of a common outcome measure able to pool the impact of both nutrition and stimulation activities.
机译:童年早期干预措施的有效性越来越多的证据,以提高儿童的增长和发展。尽管历史上,营养和刺激干预措施可能是分开交付的,但它们越来越多地被视为一揽子早期儿童干预措施,这些干预措施协同改善了生活课程的结果。但是,在不首先考虑这些干预措施的相对成本和成本效益,因此很少实现规模的实施。该地区的证据差距可能会阻止大规模实施,特别是在低收入中等收入国家。我们开展文献综述,以确定童年早期营养和发展干预措施的成本效益所知。一组预定义的搜索条例和排除条件标准化了五个数据库的搜索。搜索确定了15篇相关文章。其中,九是在高收入国家和中低收入国家的六个中的研究。文章计算营养特异性干预(n = 8)的成本效益,旨在改善儿童生长,或养育干预(刺激)以改善幼儿发育(n = 7)。没有任何文章估计了合并干预措施的成本效益。比较营养或刺激干预内的结果,或者在这些分析中使用的各种结果措施,营养和刺激干预措施在很大程度上防止了。本文突出了对低收入中等收入国家相关的进一步证据。促进研究之间的成本效益的比较,在适当的情况下,倡导往往的常见结果措施,例如避免避免避免避免避免的每年的每年的终身成本。最后,考虑到营养和刺激干预率的越来越多,鉴于所测试的刺激干预措施,对组合计划的成本效益的证据有重大需求。通过使用能够汇集营养和刺激活动的影响的共同结果措施,这也将促进。

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