Limited effectiveness with a 10‐day bismuth‐containing quadruple therapy (Pylera        <sup >??        ) in third‐line recue treatment for        <i >Helicobacter pyloriHelicobacter pylori        infection. A real‐life multicenter study

Rodríguez de Santiago Enrique; Martín de Argila de Prados Carlos; Marcos Prieto Hector Miguel; Jorge Turrión Miguel ?ngel; Barreiro Alonso Eva; Flores de Miguel Alvaro; Coba Ortiz Cristobal; Rodríguez Escaja Carlos; Pérez álvarez Gustavo; Ferre Aracil Carlos; Aguilera Castro Lara; García García de Paredes Ana; Rodríguez Pérez Antonio; Albillos Martínez Agustin

摘要

Abstract <section numbered="no" xml:id="hel12423-sec-0001"> <title type="main">Background > Helicobacter pylori antibiotic resistance is an increasing problem worldwide. Pylera ? may be an option as salvage therapy. </section> <section numbered="no" xml:id="hel12423-sec-0002"> <title type="main">Aim > To assess the effectiveness, safety, and tolerance of Pylera ? as a third‐line in clinical practice. </section> <section numbered="no" xml:id="hel12423-sec-0003"> <title type="main">Materials and Methods > This was a multicenter, observational, prospective database study in four Spanish hospitals. Consecutive H. pylori ‐infected individuals treated with Pylera ? and a proton‐pump inhibitor ( <fc>PPI</fc> ) were invited to participate if they had failed to respond to <fc>PPI</fc> ‐clarithromycin‐amoxicillin as first‐line and to levofloxacin‐amoxicillin‐ <fc>PPI</fc> as second‐line therapy. Eradication was tested 4‐8?weeks after Pylera ? using a C 13 ‐urea breath test. Treatment‐related adverse effects ( <fc>TRAE</fc> s) were assessed through a questionnaire and by reviewing databases. A questionnaire on patient satisfaction was completed in the last visit. </section> <section numbered="no" xml:id="hel12423-sec-0004"> <title type="main">Results > Of 103 subjects fulfilling the selection criteria, 101 were included in the intention‐to‐tre </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“main”XML：ID =“Hel12423-Abs-Abs-0001”> <标题类型=“main”>抽象</ title> <secueeded =“no”xml：id =“hel12423-sec-0001” > <标题类型=“main”>背景</ title> > 幽门螺杆菌</ i>抗生素抗性是全世界的增加问题。 Pylera ？</ sup>可以是抢救疗法的选项。 </ p> </部分> <部分编号=“否”XML：ID =“Hel12423-SEC-0002”> <标题类型=“MAIN”> AIM </ TITE> <P>以评估有效性，安全性，幽门β</ sup>作为临床实践中的第三行的耐受性。 </ p> </段> <部分编号=“否”XML：ID =“hel12423-sec-0003”> <标题类型=“main”>材料和方法</ title> >这是一个多中心，四个西班牙医院的观察性，前瞻性数据库研究。连续 h。幽灵</ i>用幽门β-β-β-</ sup>和质子泵抑制剂（<fc> ppi </ fc>）进行诱导的个体参加他们未能响应<fc> ppi作为第一线和左氧氟沙星 - 阿莫西林 - <FC> PPI </ FC>作为二线治疗，为二线治疗。在Pylera β</ sup>使用C 13 / sup> -urea呼气测试后测试了4-8个？通过问卷评估治疗相关的不良反应（<FC> Trae </ Fc> s），并通过审查数据库进行评估。关于患者满意度的调查问卷在最后一次访问中完成。 </ p> </段> <部分编号=“否”XML：ID =“Hel12423-SEC-0004”> <标题类型=“main”>结果</ title> > 103个科目的符合选择标准，有意在意图 - tre-tre中包含101个 </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-32409/'>《Helicobacter》</a> <b style="margin: 0 2px;">|</b><span>2017年第5期</span><b style="margin: 0 2px;">|</b><span>共7页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Rodríguez de Santiago Enrique&option=202" target="_blank" rel="nofollow">Rodríguez de Santiago Enrique;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Martín de Argila de Prados Carlos&option=202" target="_blank" rel="nofollow">Martín de Argila de Prados Carlos;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Marcos Prieto Hector Miguel&option=202" target="_blank" rel="nofollow">Marcos Prieto Hector Miguel;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Jorge Turrión Miguel ?ngel&option=202" target="_blank" rel="nofollow">Jorge Turrión Miguel ?ngel;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Barreiro Alonso Eva&option=202" target="_blank" rel="nofollow">Barreiro Alonso Eva;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Flores de Miguel Alvaro&option=202" target="_blank" rel="nofollow">Flores de Miguel Alvaro;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Coba Ortiz Cristobal&option=202" target="_blank" rel="nofollow">Coba Ortiz Cristobal;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Rodríguez Escaja Carlos&option=202" target="_blank" rel="nofollow">Rodríguez Escaja Carlos;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Pérez álvarez Gustavo&option=202" target="_blank" rel="nofollow">Pérez álvarez Gustavo;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ferre Aracil Carlos&option=202" target="_blank" rel="nofollow">Ferre Aracil Carlos;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Aguilera Castro Lara&option=202" target="_blank" rel="nofollow">Aguilera Castro Lara;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=García García de Paredes Ana&option=202" target="_blank" rel="nofollow">García García de Paredes Ana;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Rodríguez Pérez Antonio&option=202" target="_blank" rel="nofollow">Rodríguez Pérez Antonio;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Albillos Martínez Agustin&option=202" target="_blank" rel="nofollow">Albillos Martínez Agustin;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of Gastroenterology and HepatologyHospital Universitario Ramón y CajalMadrid Spain;</p> <p>Department of Gastroenterology and HepatologyHospital Universitario Ramón y CajalMadrid Spain;</p> <p>Gastroenterology departmentHospital Universitario de SalamancaSalamanca Spain;</p> <p>Department of Gastroenterology and HepatologyHospital Universitario Central de AsturiasOviedo Spain;</p> <p>Gastroenterology UnitHospital de Cabue?esGijón Spain;</p> <p>Department of Gastroenterology and HepatologyHospital Universitario Ramón y CajalMadrid Spain;</p> <p>Gastroenterology UnitHospital de Cabue?esGijón Spain;</p> <p>Department of Gastroenterology and HepatologyHospital Universitario Central de AsturiasOviedo Spain;</p> <p>Department of Gastroenterology and HepatologyHospital Universitario Central de AsturiasOviedo Spain;</p> <p>Department of Gastroenterology and HepatologyHospital Universitario Ramón y CajalMadrid Spain;</p> <p>Department of Gastroenterology and HepatologyHospital Universitario Ramón y CajalMadrid Spain;</p> <p>Department of Gastroenterology and HepatologyHospital Universitario Ramón y CajalMadrid Spain;</p> <p>Gastroenterology departmentHospital Universitario de SalamancaSalamanca Spain;</p> <p>Department of Gastroenterology and HepatologyHospital Universitario Ramón y CajalMadrid Spain;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/183.html" title="微生物学">微生物学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=bismuth&option=203" rel="nofollow">bismuth;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=helicobacter&option=203" rel="nofollow">helicobacter;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Pylera&option=203" rel="nofollow">Pylera;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=quadruple therapy&option=203" rel="nofollow">quadruple therapy;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=rescue&option=203" rel="nofollow">rescue;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=third‐line&option=203" rel="nofollow">third‐line;</a> </p> <div class="translation"> 机译：铋;幽门螺杆菌;幽门;四重疗法;救援;第三行; </div> </li> </ul> </div> </div> <div class="literature cardcommon" id="literaturereference" style="display:none"> <div class="similarity "> <h3 class="all_title" id="enpatent111">引文网络</h3> <div class="referencetab clearfix"> <ul id="referencedaohang"> <li dataid="referenceul">参考文献</li> <li dataid="citationul">引证文献</li> <li dataid="commonreferenceul">共引文献</li> <li dataid="commoncitationul">同被引文献</li> <li dataid="tworeferenceul">二级参考文献</li> <li dataid="twocitationul">二级引证文献</li> </ul> </div> <div class="reference_details" id="referenceList"> <ul id="referenceul"></ul> <ul id="citationul"></ul> <ul id="commonreferenceul"></ul> <ul id="commoncitationul"></ul> <ul id="tworeferenceul"></ul> <ul id="twocitationul"></ul> </div> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704025099462.html">Limited effectiveness with a 10‐day bismuth‐containing quadruple therapy (Pylera <sup >?? ) in third‐line recue treatment for <i >Helicobacter pyloriHelicobacter pylori infection. A real‐life multicenter study</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Rodríguez de Santiago Enrique&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Rodríguez de Santiago Enrique,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Martín de Argila de Prados Carlos&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Martín de Argila de Prados Carlos,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Marcos Prieto Hector Miguel&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Marcos Prieto Hector Miguel,</a> <a href="/journal-foreign-32409/" target="_blank" rel="nofollow" class="tuijian_authcolor">Helicobacter .</a> <span>2017</span><span>,第5期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：含有10天的铋的四重治疗（Pylera <Sup>β）的有限有效性（Pylera β），在第三线拷贝治疗中为幽门螺杆菌</ i>幽门螺杆菌感染。真实的多中心研究</span> </p> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704025099543.html">Twice-a-day PPI, tetracycline, metronidazole quadruple therapy with Pylera (R) or Lactobacillus reuteri for treatment naive or for retreatment of Helicobacter pylori. Two randomized pilot studies</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Dore Maria Pina&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Dore Maria Pina,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Bibbo Stefano&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Bibbo Stefano,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Loria Mariafrancesca&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Loria Mariafrancesca,</a> <a href="/journal-foreign-32409/" target="_blank" rel="nofollow" class="tuijian_authcolor">Helicobacter .</a> <span>2019</span><span>,第6期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：每日PPI，四环素，甲硝唑四片疗法与Pylera（r）或乳酸杆菌治疗幼稚或幽门螺杆菌的后退。两个随机试验研究</span> </p> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704024816168.html">14 day sequential therapy versus 10 day bismuth quadruple therapy containing high-dose esomeprazole in the first-line and second-line treatment of Helicobacter pylori: a multicentre, non-inferiority, randomized trial</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Liou Jyh-Ming&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Liou Jyh-Ming,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Chen Chieh-Chang&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Chen Chieh-Chang,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Fang Yu-Jen&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Fang Yu-Jen,</a> <a href="/journal-foreign-30857/" target="_blank" rel="nofollow" class="tuijian_authcolor">The Journal of Antimicrobial Chemotherapy .</a> <span>2018</span><span>,第9期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：14天顺序治疗与10天铋四人疗法含有高剂量eSomeprazole在一线和二线治疗幽门螺杆菌：多期，非劣势，随机试验</span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-conference-foreign_meeting-274085_thesis/0705013011422.html">Effectiveness of maastrikht -3 guidelines on treatment of chronic gastritis combined with helicobacter pylori infection.</a> <b>[C]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Shahmaliyev Q.Sh.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Shahmaliyev Q.Sh. </a> <a href="/conference-foreign-274085/" target="_blank" rel="nofollow" class="tuijian_authcolor">World Asthma COPD Forum .</a> <span>2011</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：Maastrikht -3治疗慢性胃炎与幽门螺杆菌感染联合治疗的有效性。</span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-journal-foreign-pmc_detail_thesis/040004018477.html">Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole Bismuth Amoxicillin and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective Multicenter Randomized Parallel-Controlled Clinical Trial in China</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yong Xie&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Yong Xie,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Zhenhua Zhu&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Zhenhua Zhu,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Jiangbin Wang&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Jiangbin Wang,</a> <span>2018</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：含低剂量雷贝拉唑铋阿莫西林和四环素的十天四联疗法是一种对抗生素耐药性高的人群幽门螺杆菌感染的有效且安全的一线治疗：一项前瞻性多中心随机平行对照的临床试验在中国</span> </p> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/open-access_resources_thesis/01000125179686.html">Modified quadruple therapy versus bismuth-containing quadruple therapy in first-line treatment of Helicobacter pylori infection in Korea; rationale and design of an open-label, multicenter, randomized controlled trial</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Hyun Lim&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Hyun Lim,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Chang Seok Bang&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Chang Seok Bang,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Woon Geon Shin&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Woon Geon Shin,</a> <span>2018</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：改良的四重治疗与含有铋的四重疗法在韩国幽门螺杆菌感染的一线治疗中;开放标签，多中心，随机对照试验的理由和设计</span> </p> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_guide-china-medicine_thesis/0201298534570.html">胶体果胶铋联合三联用药方案治疗幽门螺杆菌感染相关胃病的临床观察</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=邹广艳&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 邹广艳</a> <span> <a href="/journal-cn-6710/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 中国医药指南 </a> </span> <span> . 2022</span><span>,第4期</span> </span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chinese-journal-modern-drug-application_thesis/0201298580894.html">对幽门螺杆菌感染阳性消化性溃疡患者采取含铋四联疗法联合双歧杆菌四联活菌片治疗的效果分析</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=程杰&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 程杰</a> <span> <a href="/journal-cn-6421/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 中国现代药物应用 </a> </span> <span> . 2022</span><span>,第1期</span> </span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/academic-journal-cn_contemporary-medical-symposium_thesis/0201278006390.html">枸橼酸铋钾联合三联疗法治疗幽门螺杆菌感染所致慢性胃炎合并消化性溃疡的效果观察</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=祝元英&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 祝元英</a> <span> <a href="/journal-cn-10323/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 当代医药论丛 </a> </span> <span> . 2020</span><span>,第001期</span> </span> </div> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-journal-cn_guide-china-medicine_thesis/0201289144579.html">含枸橼酸铋钾的四联疗法治疗幽门螺杆菌感染所致消化性溃疡患者的临床效果</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张立亚&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 张立亚</a> <span> <a href="/journal-cn-6710/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 中国医药指南 </a> </span> <span> . 2020</span><span>,第036期</span> </span> </div> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-journal-cn_shanxi-medical-journal_thesis/0201270569110.html">枸橼酸铋钾阿莫西林及甲硝唑治疗幽门螺杆菌感染的效果分析</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . </a> <span> <a href="/journal-cn-6651/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 山西医药杂志 </a> </span> <span> . 2019</span><span>,第001期</span> </span> </div> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-40326_thesis/020222372211.html">复方嗜酸乳杆菌在根除幽门螺杆菌感染治疗中的疗效评价</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=TANG Jie&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . TANG Jie</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=唐捷&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,唐捷</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=LONG Yun&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,LONG Yun</a> <span> <a href="/conference-cn-40326/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 四川省医院协会药事管理委员会第十五次会员大会暨学术年会 </a> <span> <span> . 2015</span> </span> </div> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/academic-degree-domestic_mphd_thesis/020315265415.html">含胃铋镁四联方案治疗幽门螺杆菌感染的临床观察</a> <b>[A] </b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=陈艳&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 陈艳</a> <span> . 2019</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/061204358151.html">GSDMD抑制剂在制备治疗幽门螺杆菌感染的药物中的应用</a> <b>[P]</b> . <span> 中国专利： CN111529707B </span> <span> . 2021.04.23</span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06120113386445.html">梅花草提取物在制备治疗幽门螺杆菌感染疾病药物中的应用</a> <b>[P]</b> . <span> 中国专利： CN113413402A </span> <span> . 2021-09-21</span> </div> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right rightcon"> <div class="details_img cardcommon clearfix" style="margin-bottom: 10px;display:none;" > </div> </div> </div> <div id="thesis_get_original1" class="downloadBth" style="bottom: 19px;z-index: 999;" onclick="ywcd('0704025099462','4',7,2,1,'',this,24)" class="delivery" prompt="010401" title="通过人工服务将文献原文发送至邮箱" >获取原文</div> <div class="journalsub-pop-up" style="display: none"> <div class="journal-sub"> <h2>期刊订阅</h2> <img src="https://cdn.zhangqiaokeyan.com/img/loginclose.png" alt="关闭" onclick="$('.journalsub-pop-up').hide()"> <p class="pardon">抱歉，该期刊暂不可订阅，敬请期待！</p> <p class="current">目前支持订阅全部北京大学中文核心（2020）期刊目录。</p> <div style="display: flex;margin-top: 69px;justify-content: space-between;"> <div class="no-sub" onclick="$('.journalsub-pop-up').hide()">暂不订阅</div> <div class="other-sub" onclick="continueSub('from=pc-detail')">继续订阅其他期刊</div> </div> </div> </div> <div class="right_btn"> <ul> <li class="gouwuche">  </li> <li class="yijian"> <a href="javascript:void(0);" onclick="link_analysis('/mycenter/auth/complaint.html',this)" title="意见反馈">意见反馈</a> </li> <li class="top"> <a href="javascript:scrollTo(0,0);" title="回到顶部">回到顶部</a> </li> <li class="shouye"> <a href="/" title="首页">回到首页</a> </li> </ul> </div> <div class="xllindexfooter"> <div class="xllindexfootercenter"> <div class="xllindexfooterleft left" > <div class="xllindexfooterleftli"> <ul> <li><a href="/about.html" title="关于掌桥">关于掌桥</a></li> <li><a href="/help/helpmap.html" title="资源导航">资源导航</a></li> <li><a href="/help/helpguide.html" title="新手指南">新手指南</a></li> <li><a href="/help/helpcenter.html" title="常见问题">常见问题</a></li> <li><a href="/sitemap.html" title="网站地图">网站地图</a></li> <li><a href="/help/helpcenter.html?type=9" title="版权声明">版权声明</a></li> </ul> </div> <div class="xllindexfooterleft"> <p class="xllindexfooterlefteamil">客服邮箱：kefu@zhangqiaokeyan.com</p> <div class="xllindexfooterlefttcp"> <div class="xllindexfooterpoliceiimg"></div> <div class="xllindexfooterpoliceispan"> <span>京公网安备：11010802029741号 </span> <span>ICP备案号：<a href="https://beian.miit.gov.cn" rel="nofollow" target="_blank" title="ICP备案号">京ICP备15016152号-6</a></span> <span>六维联合信息科技 (北京) 有限公司©版权所有</span> </div> </div> </div> </div> <div class="xllindexfooterright left"> <ul> <li> <p style="font-weight: bold;">客服微信</p> <div></div> </li> <li> <p style="font-weight: bold;">服务号</p> <div></div> </li> </ul> </div> </div> </div> <span id="0704025099462down" data-source="7," data-out-id="3ZL6NO8NOQXLk2EC7B87MaPMANKrYrjWQppbMjzE88aIRyHJYFxm6V25BCZLNrvE," data-f-source-id="7" data-title="Limited effectiveness with a 10‐day bismuth‐containing quadruple therapy (Pylera <sup >?? ) in third‐line recue treatment for <i >Helicobacter pyloriHelicobacter pylori infection. 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Limited effectiveness with a 10‐day bismuth‐containing quadruple therapy (Pylera ?? ) in third‐line recue treatment for Helicobacter pyloriHelicobacter pylori infection. A real‐life multicenter study

摘要

Limited effectiveness with a 10‐day bismuth‐containing quadruple therapy (Pylera ^{?? ) in third‐line recue treatment for Helicobacter pyloriHelicobacter pylori infection. A real‐life multicenter study}