Use of Bone Morphogenetic Protein-2 in Molar Extraction Sockets for Immediate Implant Placement: A Prospective Case Series

摘要

This prospective case series enrolled consecutively qualifying patients that required immediate dental implant placement in large, uncontained, fresh molar extraction sites using recombinant human bone morphogentic protein-2/absorbable collagen sponge (rhBMP-2/ACS) combined with mineralized bone allograft. A total of 11 patients with 15 extraction sites missing bony walls were enrolled for treatment in this prospective case series. The clinical and radiographic effectiveness of rhBMP-2/ACS combined with mineralized bone allograft supported healing of immediately placed implants. Implants were uncovered at 4 to 6 months and were clinically and radiographically evaluated for ridge preservation and implant integration. All extraction sites exhibited ridge preservation and implant integration 1 year following restoration.