The Association Between Vitamin D Status and Pulmonary Function in Pediatric Patients With Cystic Fibrosis A Review of the Evidence

摘要

Sufficient vitamin D levels play an essential role in bone health and, more recently, in pulmonary function. Achieving sufficient vitamin D levels is challenging, especially among individuals with malabsorptive diseases, such as cystic fibrosis (CF). Cystic fibrosis is characterized by a progressive loss of pulmonary function and fat malabsorption, increasing the risk for vitamin D deficiency. After reviewing the literature for pediatric patients with CF, the association between vitamin D status and pulmonary function remains unclear. More studies are needed to evaluate whether adequate vitamin D status can assist in maintaining pulmonary function and slowing disease progression.