Evaluation of schisandra extract using sandwich-cultured human hepatocytes and b-clear (R) technology for the prediction of clinically relevant clearance interactions

Roe Amy; Jackson Jonathan; Freeman Kimberly; Friley Weslyn; Brouwer Kenneth; Black Christopher

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Evaluation of schisandra extract using sandwich-cultured human hepatocytes and b-clear (R) technology for the prediction of clinically relevant clearance interactions

机译：使用夹层培养的人肝细胞和B透明（R）技术评价Schisandra提取物用于预测临床相关的间隙相互作用

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来源
《Toxicology Letters: An International Journal Providing a Forum for Original and Pertinent Contributions in Toxicology Research 》 |2017年第s1期| 共2页
作者
Roe Amy; Jackson Jonathan; Freeman Kimberly; Friley Weslyn; Brouwer Kenneth; Black Christopher;
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作者单位

Procter &

Gamble Co Prod Safety &

Regulatory Affairs Williamstown MA USA;

Procter &

Gamble Co Prod Safety &

Regulatory Affairs Williamstown MA USA;

Procter &

Gamble Co Prod Safety &

Regulatory Affairs Williamstown MA USA;

Procter &

Gamble Co Prod Safety &

Regulatory Affairs Williamstown MA USA;

Procter &

Gamble Co Prod Safety &

Regulatory Affairs Williamstown MA USA;

Procter &

Gamble Co Prod Safety &

Regulatory Affairs Williamstown MA USA;

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原文格式 PDF
正文语种 eng
中图分类毒物学（毒理学） ;
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1. Evaluation of schisandra extract using sandwich-cultured human hepatocytes and b-clear (R) technology for the prediction of clinically relevant clearance interactions [J] . Roe Amy, Jackson Jonathan, Freeman Kimberly, Toxicology Letters: An International Journal Providing a Forum for Original and Pertinent Contributions in Toxicology Research . 2017 ,第S1期

机译：使用夹层培养的人肝细胞和B透明（R）技术评价Schisandra提取物用于预测临床相关的间隙相互作用
2. More relevant prediction for in vivo drug interaction of candesartan cilexetil on hepatic bile acid transporter BSEP using sandwich-cultured hepatocytes. [J] . Hajime Fukuda, Takeo Nakanishi, Ikumi Tamai Drug metabolism and pharmacokinetics. . 2014 ,第1期

机译：使用夹心培养的肝细胞，坎地沙坦西酯在肝胆汁酸转运蛋白BSEP上的体内药物相互作用的更相关的预测。
3. More Relevant Prediction for In Vivo Drug Interaction of Candesartan Cilexetil on Hepatic Bile Acid Transporter BSEP Using Sandwich-cultured Hepatocytes [J] . Hajime FUKUDA, Takeo NAKANISHI, Ikumi TAMAI Drug metabolism and pharmacokinetics. . 2014 ,第1期

机译：使用三明治培养的肝细胞对坎地沙坦Cilexetil在肝胆汁酸转运蛋白BSEP上体内药物相互作用的更多相关预测
4. Optimization of Human Hepatocyte Assay for Human Clearance Prediction [C] . Min Jiang, Qiuping Ye American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2012

机译：人类肝细胞测定的人类间隙预测优化
5. Mechanisms of Human Erythrocyte Clearance During Human-to-Porcine-Liver Xenoperfusion and the Assessment of Current Pre-clinical Models. [D] . Waldman, Joshua Paul. 2013

机译：人对猪肝异种灌注过程中人类红细胞清除的机制和当前临床前模型的评估。
6. Sandwich-Cultured Hepatocytes: An In Vitro Model to Evaluate Hepatobiliary Transporter-Based Drug Interactions and Hepatotoxicity [O] . Brandon Swift, Nathan D. Pfeifer, Kim L.R. Brouwer -1

机译：三明治培养的肝细胞：一种评估肝胆转运蛋白的药物相互作用和肝毒性的体外模型
7. Successful Prediction of In Vivo Hepatobiliary Clearances and Hepatic Concentrations of Rosuvastatin Using Sandwich-Cultured Rat Hepatocytes, Transporter-Expressing Cell Lines, and Quantitative Proteomics [O] . Kazuya Ishida, Mohammed Ullah, Beáta Tóth, 2017

机译：使用夹心培养的大鼠肝细胞，转运蛋白的细胞系和定量蛋白质组学，成功预测肝胆汁的肝胆汁的肝脏浓度和肝浓度

Evaluation of schisandra extract using sandwich-cultured human hepatocytes and b-clear (R) technology for the prediction of clinically relevant clearance interactions

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