Effects of balanced hydroxyethyl starch 6% (130/0.4) and albumin 5% on clot formation and glycocalyx shedding: Subgroup analysis of a prospective randomized trial

Kammerer Tobias; Huelde Nikolai; Speck Eike; Hubner Max; Crispin Alexander; Zwissler Bernhard; Conzen Peter; von Dossow Vera; Schaefer Simon Thomas; Hofmann-Kiefer Klaus; Rehm Markus

首页> 外文期刊>Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis >Effects of balanced hydroxyethyl starch 6% (130/0.4) and albumin 5% on clot formation and glycocalyx shedding: Subgroup analysis of a prospective randomized trial

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Effects of balanced hydroxyethyl starch 6% (130/0.4) and albumin 5% on clot formation and glycocalyx shedding: Subgroup analysis of a prospective randomized trial

机译：平衡羟乙基淀粉6％（130 / 0.4）和白蛋白5％对凝块形成和甘油钙的影响：亚群分析预期随机试验

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Background: Intravenous fluids can impair coagulation and affect the endothelial glycocalyx, whereas glycocalyx shedding itself can cause an impairment of clot formation and firmness. We hypothesized that hydroxyethyl starch 6% (130/0.4) has a more distinct effect on coagulation and glycocalyx shedding than albumin 5%.

机译：背景：静脉注射液会损害凝血并影响内皮甘油癌，而甘油癌脱落本身可能会导致凝块形成和坚定的损害。我们假设羟乙基淀粉6％（130 / 0.4）对凝血和甘油钙脱落的效果比白蛋白5％更为明显。

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来源
《Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis 》 |2019年第2019期| 共8页
作者
Kammerer Tobias; Huelde Nikolai; Speck Eike; Hubner Max; Crispin Alexander; Zwissler Bernhard; Conzen Peter; von Dossow Vera; Schaefer Simon Thomas; Hofmann-Kiefer Klaus; Rehm Markus;
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作者单位

Ludwig Maximilians Univ Munchen Univ Hosp Dept Anaesthesiol Marchioninistr 15 D-81377 Munich;

Ruhr Univ Bochum Inst Anesthesiol Heart &

Diabet Ctr NRW Georgstr 11 D-32545 Bad Oeynhausen;

Ludwig Maximilians Univ Munchen Univ Hosp Dept Anaesthesiol Marchioninistr 15 D-81377 Munich;

Ludwig Maximilians Univ Munchen Univ Hosp Dept Anaesthesiol Marchioninistr 15 D-81377 Munich;

Ludwig Maximilians Univ Munchen Dept Med Informat Biometry &

Epidemiol Marchioninistr 15 D-81377;

Ludwig Maximilians Univ Munchen Univ Hosp Dept Anaesthesiol Marchioninistr 15 D-81377 Munich;

Ludwig Maximilians Univ Munchen Univ Hosp Dept Anaesthesiol Marchioninistr 15 D-81377 Munich;

Ruhr Univ Bochum Inst Anesthesiol Heart &

Diabet Ctr NRW Georgstr 11 D-32545 Bad Oeynhausen;

Ludwig Maximilians Univ Munchen Univ Hosp Dept Anaesthesiol Marchioninistr 15 D-81377 Munich;

Ludwig Maximilians Univ Munchen Univ Hosp Dept Anaesthesiol Marchioninistr 15 D-81377 Munich;

Ludwig Maximilians Univ Munchen Univ Hosp Dept Anaesthesiol Marchioninistr 15 D-81377 Munich;

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原文格式 PDF
正文语种 eng
中图分类神经病学 ;
关键词
Rotational thrombelastometry; Hydroxyethyl starch; Albumin; Clot formation; Clot firmness; Volume replacement therapy;

机译：旋转血栓形成;羟乙基淀粉;白蛋白;凝块形成;凝块坚固;体积替代疗法;

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1. Effects of balanced hydroxyethyl starch 6% (130/0.4) and albumin 5% on clot formation and glycocalyx shedding: Subgroup analysis of a prospective randomized trial [J] . Kammerer Tobias, Huelde Nikolai, Speck Eike, Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis . 2019 ,第期

机译：平衡羟乙基淀粉6％（130 / 0.4）和白蛋白5％对凝块形成和甘油钙的影响：亚群分析预期随机试验
2. No Differences in Renal Function between Balanced 6% Hydroxyethyl Starch (130/0.4) and 5% Albumin for Volume Replacement Therapy in Patients Undergoing Cystectomy A Randomized Controlled Trial [J] . Kammerer Tobias, Brettner Florian, Hilferink Sebastian, Anesthesiology . 2018 ,第1期

机译：在接受膀胱切除术后随机对照试验的患者中，平衡6％羟乙基淀粉（130 / 0.4）和5％白蛋白的体积替代疗法之间的肾功能差异无差异
3. No Differences in Renal Function between Balanced 6% Hydroxyethyl Starch (130/0.4) and 5% Albumin for Volume Replacement Therapy in Patients Undergoing Cystectomy: A Randomized Controlled Trial (vol 128, pg 67, 2018) [J] . Kammerer T., Brettner F., Hilferink S., Anesthesiology . 2018 ,第4期

机译：平衡6％羟乙基淀粉（130 / 0.4）和5％白蛋白在接受膀胱切除术患者的肾功能之间的肾功能差异：随机对照试验（Vol 128，PG 67,2018）
4. The Management of Deformational Plagiocephaly: A Randomized, Prospective Analysis [C] . A. ROZZELLE, H. GILMER-HILL, J. PILITSIS, International Society of Craniofacial Surgery . 2005

机译：变形斑术的管理：随机，前瞻性分析
5. Methods in subgroup analysis: Estimation of risk and implications for randomized controlled trial design [D] . Reichmann, William Michael 2012

机译：亚组分析方法：风险评估和随机对照试验设计的意义
6. A prospective randomized clinical trial comparing the hemodynamics efficacy and safety of 6 hydroxyethyl starch 130/0.4 compared to albumin in postoperative patients undergoing pancreaticoduodenectomy [O] . SK Hong, K Kyoung, Y Kim, 2012

机译：一项前瞻性随机临床试验比较了在接受胰十二指肠切除术的术后患者中将6％羟乙基淀粉130 / 0.4与白蛋白相比的血流动力学疗效和安全性
7. Comparing the Effects of 5 Albumin and 6 Hydroxyethyl Starch 130/0.4 (Voluven) on Renal Function as Priming Solutions for Cardiopulmonary Bypass: A Randomized Double Blind Clinical Trial [O] . Mahmood Hosseinzadeh Maleki, Pooya Derakhshan, Amir Rahmanian Sharifabad, 2016

机译：比较5％白蛋白和6％羟乙基淀粉130 / 0.4（Voluven）对肾功能的影响，作为心肺旁路的引发溶液：随机双盲临床试验

Effects of balanced hydroxyethyl starch 6% (130/0.4) and albumin 5% on clot formation and glycocalyx shedding: Subgroup analysis of a prospective randomized trial

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