Hypoxia-activated prodrug: an appealing preclinical concept yet lost in clinical translation

Lindner Lars H.

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Hypoxia-activated prodrug: an appealing preclinical concept yet lost in clinical translation

机译：缺氧激活的前药：一种吸引人的临床前概念，但在临床翻译中丧失

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来源
《The lancet oncology》 |2017年第8期|共4页
作者
Lindner Lars H.;
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作者单位

Klinikum Univ Munchen Med Klin 3 Campus Grosshadern D-81377 Munich Germany;

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正文语种 eng
中图分类肿瘤学;
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1. Hypoxia-activated prodrug: an appealing preclinical concept yet lost in clinical translation [J] . Lindner Lars H. The lancet oncology . 2017,第8期

机译：缺氧激活的前药：一种吸引人的临床前概念，但在临床翻译中丧失
2. Lost in translation: the valley of death across preclinical and clinical divide – identification of problems and overcoming obstacles [J] . Attila A. Seyhan Translational Medicine Communications . 2019,第1期

机译：丢失翻译：横跨临床前和临床划分的死亡谷 - 识别问题和克服障碍
3. Lost in translation? Bridging the preclinical / clinical divide [J] . Mark Baker, J?rg M?hrle, Daren Austin Malaria Journal . 2012,第S1期

机译：迷失了翻译？弥合临床前/临床鸿沟
4. Three-Dimensional Photoacoustic Computed Tomography for Preclinical Research and Clinical Translation [C] . Li Lin, Peng Hu, Xin Tong, Conference on Photons Plus Ultrasound: Imaging and Sensing . 2021

机译：用于临床前研究和临床翻译的三维光声计算断层扫描
5. Integration of preclinical and clinical data with pharmacokinetic modeling and simulations to characterize the disposition of orally-active antiparasitic prodrugs and metabolites: Prediction of the dose-exposure relationship in humans. [D] . Yan, Zhixia. 2011

机译：临床前和临床数据与药代动力学建模和模拟的集成，以表征口服活性抗寄生虫前药和代谢物的分布：预测人类的剂量-暴露关系。
6. Lost in translation? Bridging the preclinical / clinical divide [O] . Mark Baker, Jörg Möhrle, Daren Austin 2012

机译：迷失了翻译？弥合临床前/临床鸿沟
7. Lost in translation? Bridging the preclinical / clinical divide [O] . Mark Baker, Jörg Möhrle, Daren Austin 2012

机译：迷失了翻译？弥合临床前/临床鸿沟

Hypoxia-activated prodrug: an appealing preclinical concept yet lost in clinical translation

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