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首页> 外文期刊>The Journal of heart valve disease >Treatment of Mitral Valve Regurgitation with an Open Rigid Annuloplasty Ring
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Treatment of Mitral Valve Regurgitation with an Open Rigid Annuloplasty Ring

机译:用开放式刚性环形成形术环处理二尖瓣反流

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Background and aim of the study: Annuloplasty constitutes a major operative step in the surgical treatment of degenerative mitral valve regurgitation (MR). The choice of ring structure to obtain an adequate remodeling of the mitral orifice and to respect the motion of the mitral apparatus remains the subject of debate. The study aim was to determine the clinical and echocardiographic outcome when using an open rigid ring to treat MR. Methods: A total of 129 patients (94 men, 35 women; mean age 64.5 ± 11.7 years) was referred to the authors' institution between 1997 and 2011 for the surgical management of severe MR. Patients were implanted with a modified open rigid annuloplasty ring, and also underwent anterior and/or posterior leaflet repair. The occurrence of any major adverse cardiac and cerebrovascular event (MACCE) was considered as the primary end-point and was retrospectively collected along with echocardiographic data. Results: The perioperative mortality was 1.6%. The cardiopulmonary bypass and cross-clamp times were 73.3 ± 17.1 min and 51.6 ± 13.0 min, respectively. There was one case (0.7%) of postoperative mitral systolic anterior motion. During a mean follow up period of 6.0 ± 3.1 years, 25 patients (19%) presented a MACCE. MACCE-free survival at one, five and 10 years was respectively 96.8%, 91.3%, and 61.4%. Preoperative determinants of MACCE were paroxysmal/persistent atrial fibrillation (HR 2.53; 95% CI: 1.06-6.01; p = 0.035) and age (HR 1.05; 95% CI: 1-1.09; p = 0.035). Conclusion: Mitral valve repair with an open-rigid ring offers satisfactory long-term results with a low rate of subsequent MR recurrence and reintervention. Preoperative AF is the main determinant of long-term adverse outcome.
机译:该研究的背景和目的:含环成形术在退行性二尖瓣反流(MR)的外科治疗中构成主要的操作步骤。选择环形结构以获得二尖瓣的充分重塑并尊重二尖瓣装置的运动仍然是辩论的主题。研究目的是在使用开放刚性环以治疗MR时确定临床和超声心动图结果。方法:共有129名患者(94名男子,35名女性;平均年龄为64.5±11.7岁)1997年至2011年间,1997年至2011年间的严重MR的手术管理。患者植入修饰的开放式刚性环形成形术环,也接受了前部和/或后叶修复。发生任何主要不良心脏和脑血管事件(MACCE)的发生被认为是主要终点,并回顾性地与超声心动图数据一起收集。结果:围手术期死亡率为1.6%。心肺旁路和交叉夹次数分别为73.3±17.1分钟和51.6±13.0分钟。术后二尖瓣收缩前运动有一种情况(0.7%)。在平均随访期间为6.0±3.1岁,25名患者(19%)提出了宏观。无碱生存率,五年和10年分别为96.8%,91.3%和61.4%。猕猴的术前决定例是阵发性/持续的心房颤动(HR 2.53; 95%CI:1.06-6.01; P = 0.035)和年龄(HR 1.05; 95%CI:1-1.09; P = 0.035)。结论:带开放式环的二尖瓣修复提供令人满意的长期结果,随后的先生复发和重新控制。术前af是长期不良结果的主要决定因素。

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