Heterogeneity of coordinate-based meta-analyses of neuroimaging data: an example from studies in OCD.

摘要

Two automated, coordinate-based meta-analyses of voxel-based morphometry (VBM) studies comparing individuals with obsessive-compulsive disorder (OCD) and healthy controls have been recently published, respectively, in the British Journal of Psychiatry and Neuropsychopharmacology. Surprisingly, their results are less concordant than one would have expected. We believe this is largely due to methodological differences across the studies.