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首页> 外文期刊>The American journal on addictions / >Patterns of opioid use during initial buprenorphine/naloxone treatment in relation to changes in opioid management laws in Kentucky
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Patterns of opioid use during initial buprenorphine/naloxone treatment in relation to changes in opioid management laws in Kentucky

机译:在肯塔基州阿片类药物管理法的变化中初始丁丙诺啡/纳洛酮治疗中使用的阿片类药物的模式

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Background and Objectives There is limited information on the most commonly used opioid reported at the time of presentation for treatment with buprenorphine/naloxone and the extent to which state policy may impact type of opioid use reported. Methods Retrospective study, total N ?=?of 595 from four different medical locations from January 1, 2009 to July 1, 2016 that provided buprenorphine/naloxone treatment in Louisville, Kentucky. Study aims included identifying the most commonly used opioid at the time of treatment before and after the creation of a state‐wide opioid prescribing surveillance system (ie, the 2012 House Bill 1 [HB1]), and determine the extent to which clinical setting, sex, age, and insurance type impacted type of opioid reported during the intake appointment. Results Non‐heroin opioid use decreased in the academic and private practice settings following passage of HB1, while heroin use increased in all three settings. After controlling for clinical setting and demographic characteristics, there was a significant increase in patients who reported using heroin (vs. non‐heroin opioid) (RR?=?25.00, p?≤? .001, CI?=?12.08–51.73) and a significant increase in patients who reported using opioid agonists (vs. non‐heroin opioid) (RR?=?6.56, p?≤? .001, CI?=?4.10–10.50) following enactment of HB1. Discussion and Conclusions After the passage of HB1, there was a significant increase in patients reporting heroin use and opioid agonists compared to non‐heroin opioids when presenting for treatment. Significant Significance There has been a notable shift in the opioid epidemic, which is evident in the outpatient treatment settings. (Am J Addict 2018;27:560–566)
机译:背景和目标存在有关培养培养丙甲酮/纳洛酮在介绍时报告的最常用的阿片类药物的信息有限,以及州政策可能会影响阿片类药物的类型的程度。方法回顾性研究,总N?=?来自2009年1月1日至2016年7月1日的四个不同医疗地点的595个,在肯塔基州路易斯维尔提供丁丙诺啡/纳洛酮治疗。研究旨在鉴定在创建状态的ApioID处方监测系统之前和之后鉴定治疗时最常用的阿片类药物(即2012年票据1 [HB1]),并确定临床环境的程度,入学期间报告的性别,年龄和保险型摄氏型阿片类药物。结果在HB1通过后,学术和私人实践环境中的非海洛因阿片类药物使用减少,而海洛因使用在所有三种环境中增加。在控制临床环境和人口特征后,使用海洛因(与非海洛因阿片类药物)报告的患者显着增加(RR?= 25.00,P?≤α.001,CI?=?12.08-51.73)在制定HB1后,涉及阿片类激动剂(对非海洛因阿片类药物)(RRα= 6.56,P≤≤x≤006,CI?= 4.10-10.50),显着增加。讨论和结论在HB1通过后,与非海洛因阿片类药物在提出治疗时,报告海洛因使用和阿片类激动剂的患者显着增加。表述疫情显着意义,在门诊治疗环境中是显而易见的。 (AM addict 2018; 27:560-566)

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