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3D printed biodegradable composites: An insight into mechanical properties of PLA/chitosan scaffold

机译:3D印刷可生物降解复合材料:深入了解PLA / Chitosan脚手架的机械性能

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摘要

Three-dimensional (3D) printing is a frontier manufacturing approach with great potential to benefit biomedical and patient care sectors. In the last decades, different types of biomedical materials were investigated in purpose of developing medical tools and devices. The present study attempts to assess mechanical performances (namely: tensile, compression, and flexural) of the newly developed chitosan-reinforced poly-lactic-acid (PLA) scaffolds by using fused filament fabrication (FFF) based 3D printing technology. Specifically, the effects of chitosan loading, infill density and annealing temperature on mechanical behavior of PLA composite scaffolds are investigated via design of experiments. Moreover, fracture behavior under various load types is studied with the help of selective electron microscopy. It is found that the strength of the produced composite samples depends significantly on the loading of chitosan and infill density, while annealing temperature does not affect mechanical response. Overall, the developed PLA composite scaffolds are mechanically efficient and they appear suitable for clinical purposes.
机译:三维(3D)印刷是一种前沿的制造方法,具有良好的潜力,使生物医学和患者护理部门受益。在过去的几十年中,目的是开发医疗工具和器件的针对不同类型的生物医学材料。本研究试图通过使用基于熔丝的三丝制造(FFF)的3D印刷技术来评估新开发的壳聚糖增强的多乳酸(PLA)支架的机械性能(即:拉伸,压缩和弯曲)。具体地,通过实验设计研究了壳聚糖加载,填充密度和退火温度对PLA复合支架的力学行为的影响。此外,在选择性电子显微镜的帮助下,研究了各种负载类型下的断裂行为。结果发现,所生产的复合材料样品的强度显着取决于壳聚糖的负载和填充密度,而退火温度不会影响机械响应。总的来说,开发的PLA复合支架是机械有效的,它们看起来适合临床目的。

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