Synthesis of polymacrocyclic compounds via Pd-catalyzed amination and evaluation of their derivatives as metal detectors

摘要

A mini-review is dedicated to the application of Pd(0)-catalyzed amination reactions for the synthesis of polymacrocyclic compounds of various architectures. Such molecules comprise diazacrown ether moieties or structural fragments of tri- and tetraazamacrocycles, polyamine or polyoxadiamine chains of different length and aromatic spacers. Polymacrocyclic compounds thus formed possess an increased number of coordination sites and are suitable for testing as potential receptors of metal cations. Some of these macrocyclic compounds were decorated with the exocyclic dansyl fluorophore group or were coupled with porphyrin units to form polymacrocyclic conjugates. Fluorescent spectra of these compounds were studied in the presence of various metal perchlorates and several macrocycles were found to act as chemosensors or molecular probes for such cations like Cu(II), Al(III), Cr(III).