Combining two model systems of psychosis: The effects of schizotypy and sleep deprivation on oculomotor control and psychotomimetic states

Meyh?fer Inga; Steffens Maria; Faiola Eliana; Kasparbauer Anna‐Maria; Kumari Veena; Ettinger Ulrich

摘要

Abstract > Model systems of psychosis, such as schizotypy or sleep deprivation, are valuable in informing our understanding of the etiology of the disorder and aiding the development of new treatments. Schizophrenia patients, high schizotypes, and sleep‐deprived subjects are known to share deficits in oculomotor biomarkers. Here, we aimed to further validate the schizotypy and sleep deprivation models and investigated, for the first time, their interactive effects on smooth pursuit eye movements (SPEM), prosaccades, antisaccades, predictive saccades, and measures of psychotomimetic states, anxiety, depression, and stress. To do so, n ?=?19 controls and n ?=?17 high positive schizotypes were examined after both a normal sleep night and 24 h of sleep deprivation. Schizotypes displayed higher SPEM global position error, catch‐up saccade amplitude, and increased psychotomimetic states. Sleep deprivation impaired SPEM, prosaccade, antisaccade, and predictive saccade performance and increased levels of psychotomimetic experiences. Additionally, sleep deprivation reduced SPEM gain in schizotypes but not controls. We conclude that oculomotor impairments are observed in relation to schizotypy and following sleep deprivation, supporting their utility as biomarkers in model systems of psychosis. The combination of these models with oculomotor biomarkers may be particularly fruitful in assisting the development of new antipsychotic or pro‐cognitive drugs. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“main”> <标题类型=“main”>抽象</ title> >精神病的模型系统，如斯凯曲型或睡眠剥夺，对我们对疾病的病因的理解有价值，这是有价值的新治疗的发展。已知精神分裂症患者，高斯科特型和睡眠剥夺的受试者在动血管生物标志物中分享缺陷。在这里，我们旨在进一步验证斯派比和睡眠剥夺模型，并首次调查它们对平滑追求眼球运动（SPEM），不熟悉，防御性，预测扫描和精神症，焦虑，抑郁症的措施进行互动影响和压力。为此， n </ i>？=？19个控制和 n </ i>？= 17高阳性酶学术后，在正常睡眠之夜和24小时后检查了睡眠剥夺。 Schizotypes显示出更高的Spem全球位置误差，追赶扫视幅度和增加的精神素质状态。睡眠剥夺障碍受损的Spem，ProsaCce，反震动和预测性扫视性能以及灵性体验的增加。此外，睡眠剥夺减少了斯科立息型的Spem增益，但不能控制。我们得出结论，观察到血栓溶膜和睡眠剥夺后观察到动力障碍，并在精神病模型系统中支持其实用性作为生物标志物。这些模型与血管运动生物标志物的组合可以特别富有成富有成效的，辅助开发新的抗精神病药或亲认知药物。 </ p> </ abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-30019/'>《Psychophysiology》</a> <b style="margin: 0 2px;">|</b><span>2017年第11期</span><b style="margin: 0 2px;">|</b><span>共15页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Meyh?fer Inga&option=202" target="_blank" rel="nofollow">Meyh?fer Inga;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Steffens Maria&option=202" target="_blank" rel="nofollow">Steffens Maria;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Faiola Eliana&option=202" target="_blank" rel="nofollow">Faiola Eliana;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Kasparbauer Anna‐Maria&option=202" target="_blank" rel="nofollow">Kasparbauer Anna‐Maria;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Kumari Veena&option=202" target="_blank" rel="nofollow">Kumari Veena;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ettinger Ulrich&option=202" target="_blank" rel="nofollow">Ettinger Ulrich;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of PsychologyUniversity of BonnBonn Germany;</p> <p>Department of PsychologyUniversity of BonnBonn Germany;</p> <p>Department of PsychologyUniversity of BonnBonn Germany;</p> <p>Department of PsychologyUniversity of BonnBonn Germany;</p> <p>Research &</p> <p>Development Sovereign HealthSan Clemente California;</p> <p>Department of PsychologyUniversity of BonnBonn Germany;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/1466.html" title="人体生理学">人体生理学;</a><a href="https://www.zhangqiaokeyan.com/clc/44.html" title="心理学">心理学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=antisaccade&option=203" rel="nofollow">antisaccade;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=model system&option=203" rel="nofollow">model system;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=schizophrenia&option=203" rel="nofollow">schizophrenia;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=schizotypy&option=203" rel="nofollow">schizotypy;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=sleep deprivation&option=203" rel="nofollow">sleep deprivation;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=smooth pursuit&option=203" rel="nofollow">smooth pursuit;</a> </p> <div class="translation"> 机译：反坐落片;模型系统;精神分裂症;斯凯曲型;睡眠剥夺;平稳追求; </div> </li> </ul> </div> </div> <div class="literature cardcommon" id="literaturereference" style="display:none"> <div class="similarity "> <h3 class="all_title" id="enpatent111">引文网络</h3> <div class="referencetab clearfix"> <ul id="referencedaohang"> <li dataid="referenceul">参考文献</li> <li dataid="citationul">引证文献</li> <li dataid="commonreferenceul">共引文献</li> <li dataid="commoncitationul">同被引文献</li> <li dataid="tworeferenceul">二级参考文献</li> <li dataid="twocitationul">二级引证文献</li> </ul> </div> <div class="reference_details" id="referenceList"> <ul id="referenceul"></ul> <ul id="citationul"></ul> <ul id="commonreferenceul"></ul> <ul id="commoncitationul"></ul> <ul id="tworeferenceul"></ul> <ul id="twocitationul"></ul> </div> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704024642439.html">Combining two model systems of psychosis: The effects of schizotypy and sleep deprivation on oculomotor control and psychotomimetic states</a> <b>[J]</b> . <span> <a 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Leenaars&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Cathalijn H.C. 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M.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Moses, J. M.,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext= Johnson, L. C.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> Johnson, L. C.,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext= Naitoh, P.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> Naitoh, P.,</a> <span>1974</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：睡眠阶段剥夺和总睡眠损失：对睡眠行为的影响。</span> </p> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_china-health-industry_thesis/0201213414544.html">快眼动睡眠剥夺对抑郁模型大鼠不同脑区色氨酸羟化酶和单胺氧化酶A的影响</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=朱列和&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 朱列和</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=许崇涛&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,许崇涛</a> <span> <a href="/journal-cn-5583/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 中国卫生产业 </a> </span> <span> . 2007</span><span>,第07X期</span> </span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-cn_journal-shaanxi-normal-university-natural-science-edition_thesis/0201270226362.html">两种睡眠剥夺模型对小鼠情绪和学习记忆的影响</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=刘陶&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 刘陶</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=郁婧&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,郁婧</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=钱召强&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,钱召强</a> <span> <a href="/journal-cn-4713/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 陕西师范大学学报（自然科学版） </a> </span> <span> . 2018</span><span>,第005期</span> </span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chinese-journal-biochemical-pharmaceuticals_thesis/0201242996618.html">丁苯酞注射液对动脉瘤性蛛网膜下腔出血脑血管痉挛患者血清神经特异性烯醇酶、C-反应蛋白及脂肪酸结合蛋白水平的影响</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=郑树法&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 郑树法</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=姚培森&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,姚培森</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=黄小芬&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,黄小芬</a> <span> <a href="/journal-cn-6449/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 中国生化药物杂志 </a> </span> <span> . 2015</span><span>,第010期</span> </span> </div> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chinese-journal-behavioral-medicine-brain-science_thesis/0201253824570.html">REM睡眠剥夺及精神病药物对大鼠行为的影响</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=高永利&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 高永利</a> <span> <a href="/journal-cn-6692/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 中华行为医学与脑科学杂志 </a> </span> <span> . 1996</span><span>,第003期</span> </span> </div> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-journal-cn_liuzhou-medicine_thesis/0201211770241.html">刺五加对果蝇睡眠剥夺模型睡眠及全基因表达谱影响的实验研究</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=许光辉&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 许光辉</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=李廷利&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,李廷利</a> <span> <a href="/journal-cn-20582/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 柳州医学 </a> </span> <span> . 2013</span><span>,第002期</span> </span> </div> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-27434_thesis/020221827137.html">快动眼睡眠剥夺及抗精神病药物对大鼠行为的影响</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=高永利&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 高永利</a> <span> <a href="/conference-cn-27434/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 第三届全国睡眠学术会议 </a> <span> <span> . 2004</span> </span> </div> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/academic-degree-domestic_mphd_thesis/020316265147.html">运动结合生慧汤对睡眠剥夺模型大鼠学习记忆的影响及其机制探讨</a> <b>[A] </b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=叶南&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 叶南</a> <span> . 2021</span> 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<span>机译：安全驾驶管理系统，睡眠剥夺确定设备，睡眠数据测量设备，用户识别信息输入设备，控制方法和程序 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130411192352.html">Driving safety management system, sleep deprivation detection device, sleep data measuring device, user identification input device, control method, and program</a> <b>[P]</b> . <span> 外国专利：  DE102015225251A1 </span> <span> . 2016-06-30</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：驾驶安全管理系统，睡眠剥夺检测装置，睡眠数据测定装置，用户识别输入装置，控制方法及程序 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130403524914.html">Monitoring the effects of sleep deprivation using neuronal avalanches</a> <b>[P]</b> . <span> 外国专利：  AU2019202928A1 </span> <span> . 2019-05-16</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: 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