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Repetitive transcranial magnetic stimulation over inferior frontal cortex impairs the suppression (but not expression) of action impulses during action conflict

机译:重复的经颅磁刺激在劣质前皮层损害在行动冲突期间抑制(但不表达)动作冲突

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摘要

Abstract >In the recent literature, the effects of noninvasive neurostimulation on cognitive functioning appear to lack consistency and replicability. We propose that such effects may be concealed unless dedicated, sensitive, and process‐specific dependent measures are used. The expression and subsequent suppression of response capture are often studied using conflict tasks. Response‐time distribution analyses have been argued to provide specific measures of the susceptibility to make fast impulsive response errors, as well as the proficiency of the selective suppression of these impulses. These measures of response capture and response inhibition are particularly sensitive to experimental manipulations and clinical deficiencies that are typically obfuscated in commonly used overall performance analyses. Recent work using structural and functional imaging techniques links these behavioral outcome measures to the integrity of frontostriatal networks. These studies suggest that the presupplementary motor area (pre‐SMA) is linked to the susceptibility to response capture whereas the right inferior frontal cortex (rIFC) is associated with the selective suppression of action impulses. Here, we used repetitive transcranial magnetic stimulation (rTMS) to test the causal involvement of these two cortical areas in response capture and inhibition in the Simon task. Disruption of rIFC function specifically impaired selective suppression of conflicting action tendencies, whereas the anticipated increase of fast impulsive errors after perturbing pre‐SMA function was not confirmed. These results provide a proof of principle of the notion that the selection of appropriate dependent measures is perhaps crucial to establish the effects of neurostimulation on specific cognitive functions. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译:</span><Abstract Type =“main”> <标题类型=“main”>摘要</标题> >在最近的文献中,非侵入性神经刺激对认知功能的影响似乎缺乏一致性和可复制性。我们建议使用这些效果,除非使用,敏感,以及具体的依赖措施,否则可以隐藏。通常使用冲突任务研究响应捕获的表达和随后的抑制。已经认为响应时间分布分析提供了对产生快速冲动反应误差的易感性的具体措施,以及这些冲动的选择性抑制的熟练程度。这些反应捕获和反应抑制措施对实验性操纵和临床缺陷特别敏感,通常在常用的整体性能分析中被混淆。最近使用结构和功能成像技术的工作将这些行为结果与前体网络的完整性联系起来。这些研究表明,预先设定的电机面积(Pre-SMA)与易受反应捕获的敏感性相关联,而右下额叶(RIFC)与选择性抑制的作用脉冲有关。在这里,我们使用重复的经颅磁刺激(RTMS)来测试这两个皮质区域在Simon任务中的响应捕获和抑制中的因果关系。 RIFC功能的破坏特异性受损的选择性抑制冲突的动作趋势,而未确认在扰动Pre-SMA功能后预期的快冲动误差的增加。这些结果提供了概念原则的证据,即适当的依赖措施的选择可能是至关重要的,以确定神经刺激对特异性认知功能的影响。</ p> </摘要> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-30019/'>《Psychophysiology》</a> <b style="margin: 0 2px;">|</b><span>2018年第3期</span><b style="margin: 0 2px;">|</b><span>共13页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=van Campen A. Dilene&option=202" target="_blank" rel="nofollow">van Campen A. Dilene;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Kunert Richard&option=202" target="_blank" rel="nofollow">Kunert Richard;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=van den Wildenberg Wery P. M.&option=202" target="_blank" rel="nofollow">van den Wildenberg Wery P. M.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ridderinkhof K. Richard&option=202" target="_blank" rel="nofollow">Ridderinkhof K. Richard;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of PsychologyUniversity of AmsterdamAmsterdam The Netherlands;</p> <p>Donders Institute for Brain Cognition and Behaviour Radboud UniversityNijmegen The Netherlands;</p> <p>Department of PsychologyUniversity of AmsterdamAmsterdam The Netherlands;</p> <p>Department of PsychologyUniversity of AmsterdamAmsterdam The Netherlands;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/1466.html" title="人体生理学">人体生理学;</a><a href="https://www.zhangqiaokeyan.com/clc/44.html" title="心理学">心理学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=action conflict&option=203" rel="nofollow">action conflict;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=action impulse&option=203" rel="nofollow">action impulse;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=IFC&option=203" rel="nofollow">IFC;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=inhibition&option=203" rel="nofollow">inhibition;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=pre‐SMA&option=203" rel="nofollow">pre‐SMA;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Simon task&option=203" rel="nofollow">Simon task;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=TMS&option=203" rel="nofollow">TMS;</a> </p> <div class="translation"> 机译:行动冲突;行动脉冲;IFC;抑制;Pre-SMA;SIMON任务;TMS; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704024642427.html">Repetitive transcranial magnetic stimulation over inferior frontal cortex impairs the suppression (but not expression) of action impulses during action conflict</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=van Campen A. 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Rushworth </a> <span>2007</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:冲突和动作选择过程中人额额叶皮层施加的自上而下控制的亚秒级变化:联合经颅磁刺激-脑电图研究</span> </p> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/open-access_resources_thesis/01000131751972.html">Transient Functional Suppression and Facilitation of Japanese Ideogram Writing Induced by Repetitive Transcranial Magnetic Stimulation of Posterior Inferior Temporal Cortex</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Y. Ueki&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Y. Ueki,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=T. Mima&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">T. Mima,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=K. Nakamura&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">K. Nakamura,</a> <span>2006</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:瞬态功能抑制和促进通过重复颞次皮层的重复经颅磁刺激诱导的日语思维写作</span> </p> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_world-latest-medicine-information_thesis/0201285808344.html">阈下重复经颅磁刺激前运动皮层对抽动秽语综合征的抽搐无控制作用</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Orth M.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . Orth M.</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Kirby R.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,Kirby R.</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Richardson M.P.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,Richardson M.P.</a> <span> <a href="/journal-cn-6273/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 世界核心医学期刊文摘:神经病学分册 </a> </span> <span> . 2005</span><span>,第008期</span> </span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-cn_evaluation-analysis-drug-hospitals-china_thesis/0201288797021.html">尼莫地平联合高频重复经颅磁刺激治疗皮层下非痴呆型血管性认知障碍的临床疗效研究</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=黄芳&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 黄芳</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=丁玲&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,丁玲</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=陈旭&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,陈旭</a> <span> <a href="/journal-cn-6444/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 中国医院用药评价与分析 </a> </span> <span> . 2021</span><span>,第002期</span> </span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/academic-journal-cn_contemporary-medicine_thesis/0201282248496.html">重复经颅磁刺激对急性期脑梗死患者生活质量及皮层兴奋性的影响</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=罗鸿波&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 罗鸿波</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=包章丽&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,包章丽</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=邱婷婷&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,邱婷婷</a> <span> <a href="/journal-cn-10321/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 当代医学 </a> </span> <span> . 2020</span><span>,第036期</span> </span> </div> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-journal-cn_journal-shanghai-university-sport_thesis/0201232452237.html">高频重复经颅磁刺激提高运动皮层兴奋性的研究</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=刘运洲&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 刘运洲</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张忠秋&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,张忠秋</a> <span> <a href="/journal-cn-3718/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 上海体育学院学报 </a> </span> <span> . 2010</span><span>,第005期</span> </span> </div> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-journal-cn_china-sport-science-technology_thesis/0201230414921.html">低频重复经颅磁刺激(rTMS)降低运动皮层兴奋性的研究</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=刘运洲&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 刘运洲</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张忠秋&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,张忠秋</a> <span> <a href="/journal-cn-3613/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 中国体育科技 </a> </span> <span> . 2010</span><span>,第004期</span> </span> </div> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-40849_thesis/020222465736.html">高频和低频重复经颅磁刺激对帕金森患者皮层兴奋度、运动和运动表现的影响</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Margaret Mak&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . Margaret Mak</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Margaret Mak&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,Margaret Mak</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Chan Poh Choo&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,Chan Poh Choo</a> <span> <a href="/conference-cn-40849/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 第十一届北京国际康复论坛 </a> <span> <span> . 2016</span> </span> </div> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/academic-degree-domestic_mphd_thesis/02031874030.html">1.三重经颅磁刺激技术对肌萎缩侧索硬化症上运动神经元损害的评价;2.重复经颅磁刺激对肌萎缩侧索硬化症的治疗研究</a> <b>[A] </b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=王悦&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 王悦</a> <span> . 2010</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/06130404076067.html">TRANSCRANIAL MAGNETIC STIMULATION CIRCUIT, TRANSCRANIAL MAGNETIC STIMULATOR AND MAGNETIC IMPULSE GENERATION METHOD THEREOF</a> <b>[P]</b> . <span> 外国专利: <!-- 美国专利: --> US2019030357A1 </span> <span> . 2019-01-31</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:跨磁激励电路,跨磁激励器及其磁脉冲产生方法 </span> </p> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06130401216146.html">METHOD FOR STIMULATING CREATIVITY USING REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (RTMS)</a> <b>[P]</b> . <span> 外国专利: <!-- --> PT109800B </span> <span> . 2020-05-22</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:使用重复性经颅磁刺激(RTMS)刺激创造力的方法 </span> </p> </li> <li> <div> <b>3. 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