Multicomponent Fabrication of Bone-Like Composite Materials Using Chitosan/PMMA-co-PHEMA/Nano-Hydroxyapatite

摘要

In this paper, we report a simple approach for the fabrication of bone-like composite materials (BCMs) by blending chitosan (CTS), a natural polysaccharide, nano-hydroxyapatite as bone mineral, and polymethylmethacrylate-co-polyhydroxyethy lmethacrylate (PMMA-co-PHEMA) as bone cement. Fourier transform infrared spectroscopy and X-ray diffraction (XRD) studies were performed to determine the components of composites. Scanning electron microscopy study of composites revealed a well-dispersed flake-like structure with increasing content of PMMA-co-PHEMA. The water-uptake ability of the BCMs was also found to increase with increasing the PMMA-co-PHEMA content. Study of mechanical properties revealed that the Young's modulus and stiffness increased significantly after the addition of PMMA-co-PHEMA in BCMs compared with CTS-HAP blend.