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首页> 外文期刊>Physical review, E >Hyperuniform flow fields resulting from hyperuniform configurations of circular disks
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Hyperuniform flow fields resulting from hyperuniform configurations of circular disks

机译:由圆形磁盘的超型配置产生的超晶体流场

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摘要

Motivated by cancer cell capture and sorting applications, we investigate the scalar velocity field of twodimensional (2D) laminar flows through configurations of fixed congruent circular disks with a disordered hyperuniform (HU) distribution of the disk centers. Disordered HU many-particle systems suppress large-scale density fluctuations like perfect crystals and yet possess no Bragg peaks, and are endowed with many novel physical properties. Here, we generate 2D HU configurations of congruent nonoverlapping (hard) circular disks with various packing densities via Monte Carlo simulations and obtain the corresponding scalar velocity fields of laminar flows via the lattice Boltzmann method. Using numerical spectral analysis, we find that hyperuniform configurations of the disks can lead to hyperuniform flow fields for a certain range of disk packing fraction Φ and normalized flow rate q over porosity ε = 1 - Φ. The degree of hyperuniformity of the flow fields, as quantified via the spectral density value at the zero-wave-number limit, reduces as Φ and q increase and eventually the fields become nonhyperuniform. The transition from HU flow fields to non-HU fields as Φ and q vary is captured using a “phase diagram.” For purpose of comparison, disordered nonhyperuniform configurations of circular disks are generated via the random sequential addition process and the resulting flow field is found to be nonhyperuniform. To complement our numerical analysis, we show analytically that HU configurations of circular disks, in the dilute (low-packing-density) limit, lead to HU flow field. Our findings have implications in the design and optimization of microfluidic chips for capture and differentiation of subpopulations in circulating tumor cells.
机译:通过癌细胞捕获和分拣应用的激励,我们研究了TwoDimensional(2D)层流的标量速度场,通过固定的一致圆盘的配置,其中磁盘中心的无序超细(HU)分布。无序的HU多粒子系统抑制了像完美晶体的大规模密度波动,但没有BRAGG峰,并且赋予许多新颖的物理性质。在这里,我们通过蒙特卡罗模拟生成一致的非全部循环(硬)圆盘的2D HU配置,并通过晶格Boltzmann方法获得层流的相应标量速度场。使用数值光谱分析,我们发现盘的超型配置可以导致一定范围的磁盘填料分数φ和归一化流量q通过孔隙率ε= 1 - φ的圆形流场。通过零波数限制的光谱密度值量化的流场的超速度,随着φ和Q增加而降低,最终域变为非血管。使用“相图”捕获从HU流场到非HU字段的转换为φ和q变化。出于比较的目的,通过随机顺序添加过程产生圆盘的无序的非咽部配置,并且发现所得流场是非血管的。为了补充我们的数值分析,我们在分析上显示了圆形磁盘的HU配置,在稀释(低包装密度)限制,导致HU流场。我们的研究结果对微流体芯片的设计和优化有影响来捕获和分化循环肿瘤细胞中的群体。

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