Combination of SEDDS and Preactivated Thiomer Technology: Incorporation of a Preactivated Thiolated Amphiphilic Polymer into Self-Emulsifying Delivery Systems

Hetenyi Gergely; Griesser Janine; Nardin Isabelle; Bernkop-Schnuerch Andreas

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Combination of SEDDS and Preactivated Thiomer Technology: Incorporation of a Preactivated Thiolated Amphiphilic Polymer into Self-Emulsifying Delivery Systems

机译：静止和妊娠巯基技术的组合：将预活性的硫醇两亲聚合物掺入自乳化递送系统中

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摘要

The aim of the study was to create novel mucoadhesive drug delivery systems by incorporating amphiphilic hydrophobically modified, thiolated and preactivated polymers (preactivated thiomers) into self-emulsifying drug delivery systems (SEDDS).

机译：该研究的目的是通过将两亲的疏水改性的，硫酸硫化和预活化的聚合物（预活性的巯基）掺入自乳化药物递送系统（SEDDS）来创造新的粘膜粘附药物递送系统。

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来源
《Pharmaceutical research》 |2017年第6期|共9页
作者
Hetenyi Gergely; Griesser Janine; Nardin Isabelle; Bernkop-Schnuerch Andreas;
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作者单位

Thiomatrix Forsch &

Beratungs GmbH Innsbruck Austria;

Thiomatrix Forsch &

Beratungs GmbH Innsbruck Austria;

Thiomatrix Forsch &

Beratungs GmbH Innsbruck Austria;

Thiomatrix Forsch &

Beratungs GmbH Innsbruck Austria;

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原文格式 PDF
正文语种 eng
中图分类生药学（天然药物学）;
关键词
mucoadhesive drug delivery; mucoadhesive SEDDS; nanocarrier; preactivated thiomer; self-emulsifying drug delivery systems;

机译：粘膜粘附药物递送;粘膜粘附潜水;纳米载波;失活的巯基;自乳化药物递送系统;

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1. Combination of SEDDS and Preactivated Thiomer Technology: Incorporation of a Preactivated Thiolated Amphiphilic Polymer into Self-Emulsifying Delivery Systems [J] . Hetenyi Gergely, Griesser Janine, Nardin Isabelle, Pharmaceutical research . 2017,第6期

机译：静止和妊娠巯基技术的组合：将预活性的硫醇两亲聚合物掺入自乳化递送系统中
2. Preactivated thiolated glycogen as mucoadhesive polymer for drug delivery [J] . Mara Perrone, Antonio Lopalco, Angela Lopedota, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2017,第期

机译：作为药物递送的粘膜粘附聚合物预活泼的硫醇化糖原
3. Preactivated thiomers for intranasal delivery of apomorphine: In vitro and in vivo evaluation [J] . Netsomboon Kesinee, Partenhauser Alexandra, Rohrer Julia, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2016,第Null期

机译：用于鼻内递送阿扑吗啡的预活化硫代聚合物：体外和体内评估
4. Formulation of Peppermint Oil in a Self-Emulsifying Drug Delivery System (SEDDS) forOral Administration [C] . Cornelia M. Keck, Rainer H. Mueller Controlled Release Society Annual Meeting and Exposition . 2007

机译：在自乳化药物递送系统（SEDDS）中配制薄荷油用于口服
5. Formulation and in-vitro and in-vivo testing of a phenytoin self-emulsifying drug delivery system (SEDDS). [D] . Atef, Eman. 2004

机译：苯妥英自乳化药物递送系统（SEDDS）的配制以及体外和体内测试。
6. Preactivated thiomers as mucoadhesive polymers for drug delivery [O] . Javed Iqbal, Gul Shahnaz, Sarah Dünnhaupt, -1

机译：预活化的硫代聚合物作为用于药物输送的粘膜粘附聚合物
7. Preactivated thiomers as mucoadhesive polymers for drug delivery [O] . Iqbal, Javed, Shahnaz, Gul, Dünnhaupt, Sarah, 2012

机译：预活化的硫代聚合物作为用于药物输送的粘膜粘附聚合物

Combination of SEDDS and Preactivated Thiomer Technology: Incorporation of a Preactivated Thiolated Amphiphilic Polymer into Self-Emulsifying Delivery Systems

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