Hemophagocytic Lymphohistiocytosis in a Newborn Presenting as “Blueberry Muffin Baby”

摘要

Abstract Hemophagocytic lymphohistiocytosis ( HLH ) is a rare, life‐threatening hyperinflammatory syndrome characterized by uncontrolled activation and proliferation of proinflammatory cytokines. Initial presentation commonly includes fever, hepatosplenomegaly, and pancytopenia; 6 to 65% of cases also have a concurrent cutaneous eruption. We present the case of a 6‐day‐old premature infant boy with congenital severe thrombocytopenia, anemia, and hepatosplenomegaly who presented with several cutaneous violaceous papules and nodules and was found to have HLH .