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Projecting the impact of hypothetical early life interventions on adiposity in children living in low‐income households

机译:预测假设早期生命干预对居住在低收入家庭儿童肥胖的影响

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Summary <section xml:id="ijpo12157-sec-0001" numbered="no"> <title type="main">Background xml:id="ijpo12157-para-0017">It is difficult to evaluate the effectiveness of interventions aimed at reducing early childhood obesity using randomized trials. <section xml:id="ijpo12157-para-0018"> <title type="main">Objective xml:id="ijpo12157-para-0019">To illustrate how observational data can be analysed using causal inference methods to estimate the potential impact of behavioural ‘interventions’ on early childhood adiposity. </section> <section xml:id="ijpo12157-sec-0002" numbered="no"> <title type="main">Methods xml:id="ijpo12157-para-0020">We used longitudinal data from 1054 children 1–5?years old enrolled in the Special Supplemental Nutrition Program for Women, Infants and Children and followed (WIC) from 2008 to 2010 for a mean duration of 23?months. The data came from a random sample of WIC families living in Los Angeles County in 2008. We used the parametric g‐formula to estimate the impact of various hypothetical behavioural interventions. </section> <section xml:id="ijpo12157-sec-0003" numbered="no"> <title type="main">Results xml:id="ijpo12157-para-0021">Adjusted mean weight‐for‐height Z score at the end of follow‐up was 0.73 (95% CI 0.65, 0.81) under no intervention and 0.63 (95% CI 0.38, 0.87) for all interventions given jointly. Exclusive breastfeeding for 6?months or longer was the most effective intervention [population mean difference?=??0.11 (95% CI ?0.22, 0.01)]. Other interventions had little or no effect. </section> <section xml:id="ijpo12157-sec-0004" numbered="no"> <title type="main">Conclusions xml:id="ijpo12157-para-0022">Compared with interventions promoting healthy eating and physical activity behaviours, breastfeeding was more effective in reducing obesity risk in children aged 1–5?years. When carefully applied, causal inference methods may offer viable alternatives to randomized trials in etiologic and evaluation research. </section> </section> </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译:</span><Abstract XMLNS =“http://www.wiley.com/namespaces/wiley”type =“main”xml:id =“ijpo12157-abs-abs-0001”> <标题类型=“main”>摘要</ title> <部分XML:ID =“IJPO12157-SEC-0001”编号=“否”> <标题类型=“main”>背景</ title> xml:id =“ijpo12157-para-0017”>很难评估旨在使用随机试验减少幼儿肥胖症的干预的有效性。</ p> <第XML:ID =“IJPO12157-ar-0018”> <标题类型=“main”>目标</ title> XML:ID =“ijpo12157-para-0019”>说明如何使用因果推断方法分析观察数据,以估计行为“干预”在早期童年肥胖上的潜在影响。</ p> </段> <章节XML:ID = “IJPO12157-SEC-0002”编号=“否”> <标题类型=“main”>方法</ title> XML:ID =“IJPO12157-PARA-0020”>我们使用了1054个孩子的纵向数据1-5 ?年龄在2008年到2010年的女性,婴儿和儿童参加了妇女,婴儿和儿童的特殊补充营养计划,并遵循(WIC) n持续​​时间为23个月。这些数据来自2008年居住在洛杉矶县的WIC系列的随机样本。我们使用参数型G-Farmany来估计各种假设行为干预的影响。</ p> </ section> <section XML:ID =“ IJPO12157-SEC-0003“编号=”否“> <标题类型=”main“>结果</ title> xml:id =”ijpo12157-para-0021“>调整后的平均重量z z分数随干预的情况下,随访的后续末期为0.73(95%CI 0.65,0.81),所有干预措施都无干预和0.63(95%CI 0.38,0.87)。 6?几个月或更长时间的独家母乳喂养是最有效的干预[人口平均差异吗?= ?? 0.11(95%CI?0.22,0.01)]。其他干预措施很少或根本没有效果。</ p> </ section> <secto xml:id =“ijpo12157-sec-0004”编号=“否”> <标题类型=“main”>结论</ title> XML:ID =“IJPO12157-PARA-0022”>与促进健康饮食和身体活动行为的干预措施相比,母乳喂养更有效地减少1-5岁儿童的肥胖风险。仔细应用时,因果推断方法可以在病因和评估研究中提供可随机试验的可行替代品。</ p> </ section> </ section> </摘要> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-28988/'>《Pediatric obesity.》</a> <b style="margin: 0 2px;">|</b><span>2017年第5期</span><b style="margin: 0 2px;">|</b><span>共8页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Nianogo Roch A.&option=202" target="_blank" rel="nofollow">Nianogo Roch A.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Wang May C.&option=202" target="_blank" rel="nofollow">Wang May C.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Wang Aolin&option=202" target="_blank" rel="nofollow">Wang Aolin;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Nobari Tabashir Z.&option=202" target="_blank" rel="nofollow">Nobari Tabashir Z.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Crespi Catherine M.&option=202" target="_blank" rel="nofollow">Crespi Catherine M.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Whaley Shannon E.&option=202" target="_blank" rel="nofollow">Whaley Shannon E.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Arah Onyebuchi A.&option=202" target="_blank" rel="nofollow">Arah Onyebuchi A.;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of Epidemiology Fielding School of Public HealthUniversity of California Los Angeles;</p> <p>California Center for Population Research UCLALos Angeles USA;</p> <p>Department of Epidemiology Fielding School of Public HealthUniversity of California Los Angeles;</p> <p>California Center for Population Research UCLALos Angeles USA;</p> <p>Department of Biostatistics UCLA School of Public HealthLos Angeles USA;</p> <p>Research and Evaluation UnitPublic Health Foundation Enterprises — Special Supplemental Nutrition;</p> <p>Department of Epidemiology Fielding School of Public HealthUniversity of California Los Angeles;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/198.html" title="儿科学">儿科学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=adiposity&option=203" rel="nofollow">adiposity;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=breastfeeding&option=203" rel="nofollow">breastfeeding;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=causal inference&option=203" rel="nofollow">causal inference;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=childhood obesity&option=203" rel="nofollow">childhood obesity;</a> </p> <div class="translation"> 机译:肥胖;母乳喂养;因果推断;儿童肥胖; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704024399152.html">Projecting the impact of hypothetical early life interventions on adiposity in children living in low‐income households</a> <b>[J]</b> . <span> <a 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