Upregulation of the C/EBP beta LAP isoform could be due to decreased TNFAIP3/TNIP1 expression in the peripheral blood mononuclear cells of patients with systemic lupus erythematosus

Qian Tian; Chen Fangru; Shi Xiaowei; Li Jian; Li Min; Chen Yan; Hao Fei; Zhang Dongmei

首页> 外文期刊>Modern rheumatology >Upregulation of the C/EBP beta LAP isoform could be due to decreased TNFAIP3/TNIP1 expression in the peripheral blood mononuclear cells of patients with systemic lupus erythematosus

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Upregulation of the C/EBP beta LAP isoform could be due to decreased TNFAIP3/TNIP1 expression in the peripheral blood mononuclear cells of patients with systemic lupus erythematosus

机译：C / EBPβ圈同种型的上调可能是由于Systemic鼠红斑狼疮患者外周血单核细胞中的TNFAIP3 / TNIP1表达减少

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Objectives: We aimed to examine CCAAT/enhancer-binding protein (C/EBP ), TNF-alpha-induced protein 3 (TNFAIP3), and TNFAIP3-interacting protein 1 (TNIP1) expression in peripheral blood mononuclear cells (PBMCs) of systemic lupus erythematosus (SLE) patients to assess their relationship in SLE pathogenesis.

机译：目的：我们的目的是在全身狼疮的外周血单核细胞（PBMC）中检查CCAAT /增强剂结合蛋白（C / EBP），TNF-α诱导的蛋白3（TNFAIP3）和TNFAIP3相互作用蛋白1（TNIP1）表达红斑（SLE）患者评估他们在SLE发病机制中的关系。

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来源
《Modern rheumatology 》 |2017年第4期| 共7页
作者
Qian Tian; Chen Fangru; Shi Xiaowei; Li Jian; Li Min; Chen Yan; Hao Fei; Zhang Dongmei;
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作者单位

Third Mil Med Univ Southwest Hosp Dept Dermatol Chongqing 400038 Peoples R China;

Guilin Med Univ Dept Dermatol Affiliated Hosp Guilin Peoples R China;

Shenyang Mil Area Command Dept Dermatol Gen Hosp Shenyang Liaoning Peoples R China;

Third Mil Med Univ Southwest Hosp Dept Dermatol Chongqing 400038 Peoples R China;

Third Mil Med Univ Southwest Hosp Dept Dermatol Chongqing 400038 Peoples R China;

Kunming Gen Hosp Chengdu Mil Reg Dept Dermatol Kunming Yunnan Peoples R China;

Third Mil Med Univ Southwest Hosp Dept Dermatol Chongqing 400038 Peoples R China;

Third Mil Med Univ Southwest Hosp Dept Dermatol Chongqing 400038 Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类免疫性疾病 ;
关键词
Autoimmunity; CCAAT/enhancer-binding protein beta; SLE; TNF-alpha-induced protein 3; TNFAIP3-interacting protein 1;

机译：自身免疫;CCAAT /增强剂结合蛋白β;SLE;TNF-α诱导的蛋白3;TNFAIP3 - 相互作用蛋白1;

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专利

1. Upregulation of the C/EBP beta LAP isoform could be due to decreased TNFAIP3/TNIP1 expression in the peripheral blood mononuclear cells of patients with systemic lupus erythematosus [J] . Qian Tian, Chen Fangru, Shi Xiaowei, Modern rheumatology . 2017 ,第4期

机译：C / EBPβ圈同种型的上调可能是由于Systemic鼠红斑狼疮患者外周血单核细胞中的TNFAIP3 / TNIP1表达减少
2. C/EBP mRNA expression is upregulated and positively correlated with the expression of TNIP1/TNFAIP3 in peripheral blood mononuclear cells from patients with systemic lupus erythematosus [J] . Qian Tian, Chen Yan, Shi Xiaowei, Experimental and therapeutic medicine . 2016 ,第4aPta1期

机译：C / EBP mRNA表达与来自Systemic Lupus患者的外周血单核细胞中TNIP1 / TNFAIP3的表达呈正相关
3. Decreased mrna expression of two FOXP3 isoforms in peripheral blood mononuclear cells from patients with rheumatoid arthritis and systemic lupus erythematosus [J] . SuzukiK., SetoyamaY., YoshimotoK., International journal of immunopathology and pharmacology. . 2011 ,第1期

机译：类风湿性关节炎和系统性红斑狼疮患者外周血单个核细胞中两种FOXP3同工型的mRNA表达降低
4. Effects of glucocorticoids on expression of CD4+ Foxp3+ T cell in patients with systemic lupus erythematosus [C] . Sheng-nan Zhao, Ya-yi Hou, Ling-yun Sun International Forum on Progress on Post-Genome Technologies(5'IFPT); 20070910-11; Suzhou(CN) . 2007

机译：糖皮质激素对系统性红斑狼疮患者CD4 + Foxp3 + T细胞表达的影响
5. In vivo Assessment of Bone Microarchitecture and Bone Strength in Systemic Lupus Erythematosus Patients by High-Resolution Peripheral Quantitative Computed Tomography and Finite Element Analysis [D] . Tang, Xiaolin. 2013

机译：高分辨率外周定量CT和有限元分析技术评估系统性红斑狼疮患者的骨微结构和骨强度
6. C/EBP β mRNA expression is upregulated and positively correlated with the expression of TNIP1/TNFAIP3 in peripheral blood mononuclear cells from patients with systemic lupus erythematosus [O] . Tian Qian, Yan Chen, Xiaowei Shi, -1

机译：系统性红斑狼疮患者外周血单个核细胞中C / EBPβmRNA表达上调并与TNIP1 / TNFAIP3表达正相关
7. C/EBP β mRNA expression is upregulated and positively correlated with the expression of TNIP1/TNFAIP3 in peripheral blood mononuclear cells from patients with systemic lupus erythematosus [O] . Tian Qian, Yan Chen, Xiaowei Shi, 2016

机译：C /EBPβmRNA表达是上调的，并与来自Systemic Lupus红斑狼疮患者的外周血单核细胞中的TNIP1 / TNFAIP3的表达呈正相关

Upregulation of the C/EBP beta LAP isoform could be due to decreased TNFAIP3/TNIP1 expression in the peripheral blood mononuclear cells of patients with systemic lupus erythematosus

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