Preliminary results: use of multi-hole injection nails for intramedullary nailing with simultaneous bone cement injection in long-bone metastasis

摘要

ObjectiveFor symptomatic metastasis of the long bones, intramedullary nailing has been the most accepted fixation method. Intramedullary nailing has effective control of pain, perioperative bleeding, and local tumor progression by augmentation with bone cement around the nail. Here, we report the preliminary results of a new surgical implant that allows for simultaneous injection of bone cement while inserting a percutaneous, flexible intramedullary nail.Materials and methodsWe performed palliative surgeries for long-bone metastasis using a multi-hole injection nail (MIN) with multiple side holes in the distal one third. When the nail tip entered the metastatic cancer lesion, the bone cement injection was started, and continued until the nail was completely seated. Ten patients with advanced cancer underwent palliative surgery using the new implant with simultaneous bone cement injection for humeral (n=4), femoral (n=4), and tibial (n=2) metastases.ResultsThe mean operative time was 42min (range, 36-52min). The mean length of the injection nail was 23.0cm (range, 18.0-33.0cm), and the mean volume of cement was 28.0ml (range, 14.0-40.0ml). Marked pain palliation (p0.001) and functional recovery (p=0.01) were verified. The mean Musculoskeletal Tumor Society (MSTS) functional score improved significantly from 12.5 at 6weeks preoperatively, to 24.9 postoperatively. No acute postoperative complications, including cement embolism, occurred.ConclusionThis minimally invasive surgical method with MIN could be useful for stabilization of long-bone metastases in patients with advanced cancer.