Effects of Anion Charge on the Biological Activity of Keggin Heteropoly Acids

摘要

This paper reports a study of the inhibitory and immunomodulating activity of phosphoric and silicon heteropoly acids with Keggin anions ([XM(1)(12 - n)M(2)(n)O-40](-m), where X = P, Si; M = Mo, W, and V; m = 3, 4, 5) toward human embryonic fibroblast cells using MTT and polymerase chain reaction techniques. The correlation between the inhibitory activity of heteropoly acids and their anion charge has been shown and interpreted.