Predictive Accuracy of Serial Transvaginal Cervical Lengths and Quantitative Vaginal Fetal Fibronectin Levels for Spontaneous Preterm Birth Among Nulliparous Women

摘要

Prediction of spontaneous preterm birth, a leading cause of infant mortality, depends in practice largely on a history of previous birth, and the risk for first time mothers and nulliparous women is more difficult to assess. The aim of this study was to assess the reliability of serial transvaginal cervical length (CL) and quantitative fetal fibronectin (fFN) measurements in predicting spontaneous preterm birth (before 37 weeks) in a large, prospective cohort of nulliparous women.