Refractory asthma phenotyping based on immunoglobulin E levels and eosinophilic counts: A real life study

Lababidi Hani M. S.; AlSowayigh Omar M.; BinHowemel Samar F.; AlReshaid Khoolod M.; Alotaiq Sultan A.; Bahnassay Ahmed A.

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Refractory asthma phenotyping based on immunoglobulin E levels and eosinophilic counts: A real life study

机译：基于免疫球蛋白E水平和嗜酸性粒细胞计数的难治性哮喘表型：真实研究

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Background: Asthma is an inflammatory heterogeneous disease with variable severity. The serum IgE level and Eosinophilic count have been used as biomarkers to define treatment strategies with biological agents in severe refractory asthma.

机译：背景：哮喘是一种具有可变严重程度的炎症异质疾病。血清IgE水平和嗜酸性粒细胞计数已被用作生物标志物，以定义具有严重难治性哮喘的生物药物的治疗策略。

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来源
《Respiratory medicine》 |2019年第2019期|共4页
作者
Lababidi Hani M. S.; AlSowayigh Omar M.; BinHowemel Samar F.; AlReshaid Khoolod M.; Alotaiq Sultan A.; Bahnassay Ahmed A.;
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作者单位

King Fahad Med City Pulm &

Crit Care Dept Riyadh Saudi Arabia;

King Faisal Univ Coll Med Alahsa Saudi Arabia;

AlMaarefa Univ Coll Med Riyadh Saudi Arabia;

AlMaarefa Univ Coll Med Riyadh Saudi Arabia;

Imam Mohammad Ibn Saud Islamic Univ Coll Med Riyadh Saudi Arabia;

King Fahad Med City Fac Med Riyadh Saudi Arabia;

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原文格式 PDF
正文语种 eng
中图分类呼吸系及胸部疾病;
关键词
Refractory asthma; Severe asthma; Immunoglobulin E; IgE; Eosinophils; Asthma control test (ACT); Biological therapy; anti-IgE; Anti IL-5; Real life;

机译：难治性哮喘;严重的哮喘;免疫球蛋白E;IgE;嗜酸性粒细胞;哮喘控制测试（ACT）;生物疗法;抗IgE;反IL-5;现实生活;

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专利

1. Refractory asthma phenotyping based on immunoglobulin E levels and eosinophilic counts: A real life study [J] . Lababidi Hani M. S., AlSowayigh Omar M., BinHowemel Samar F., Respiratory medicine . 2019,第期

机译：基于免疫球蛋白E水平和嗜酸性粒细胞计数的难治性哮喘表型：真实研究
2. Real-life effectiveness of mepolizumab in patients with severe refractory eosinophilic asthma and multiple comorbidities [J] . Claudia Crimi, Raffaele Campisi, Giulia Cacopardo, World Allergy Organization Journal . 2020,第9期

机译：严重耐火性嗜酸性哮喘患者莫博列姆布的现实生活效应和多种合并症
3. Mepolizumab improves sino-nasal symptoms and asthma control in severe eosinophilic asthma patients with chronic rhinosinusitis and nasal polyps: a 12-month real-life study [J] . Aikaterini Detoraki, Eugenio Tremante, Maria D’Amato, Therapeutic advances in respiratory disease. . 2021,第a期

机译：Mepolizumab在严重嗜酸性哮喘患者慢性鼻窦炎和鼻息肉中改善中鼻症状和哮喘控制：一个12个月的真实研究
4. Sputum Eosinophil Counts and Eosinophil Cationic Protein (ECP) Levels in Cough-Variant Asthma and in Classic Asthma, and Their Relationships to Airway Hypersensitivity or Maximal Airway Response to Methacholine [C] . Young Yoo, Young Yull Koh, Hee Kang Asia Pacific Congress of Allergology and Clinical Immunology . 2004

机译：痰嗜酸性粒细胞计数和嗜酸铈粒细胞阳离子蛋白（ECP）水平在咳嗽变异哮喘和经典的哮喘，以及它们与气道超敏反应或最大气道对甲磺酸的关系的关系
5. Acquired Low Immunoglobulin Levels and Risk of Clinically Relevant Infection in Adult Patients with Systemic Lupus Erythematosus Cohort Study [D] . Almaghlouth, Ibrahim Ali S. 2019

机译：在成人狼疮患者中获得低免疫球蛋白水平和临床相关感染的风险红斑狼疮队列队列研究
6. Real-life effectiveness of mepolizumab in patients with severe refractory eosinophilic asthma and multiple comorbidities [O] . Claudia Crimi, Raffaele Campisi, Giulia Cacopardo, 2020

机译：严重耐火性嗜酸性哮喘患者莫博列姆布的现实生活效应和多种合并症
7. Real-life effectiveness of mepolizumab in patients with severe refractory eosinophilic asthma and multiple comorbidities [O] . Claudia Crimi, Raffaele Campisi, Giulia Cacopardo, 2020

机译：严重耐火性嗜酸性哮喘患者莫博列姆布的现实生活效应和多种合并症

Refractory asthma phenotyping based on immunoglobulin E levels and eosinophilic counts: A real life study

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