The combination of the blood based tumor biomarkers cytokeratin 19 fragments (CYFRA 21-1) and carcinoembryonic antigen (CEA) as a potential predictor of benefit from adjuvant chemotherapy in early stage squamous cell carcinoma of the lung (SCC)

Muley Thomas; Rolny Vinzent; He Ying; Wehnl Birgit; Escherich Achim; Warth Arne; Stolp Christa; Schneider Marc A.; Dienemann Hendrik; Meister Michael; Herth Felix J.; Dayyani Farshid

首页> 外文期刊>Lung cancer: Journal of the International Association for the Study of Lung Cancer >The combination of the blood based tumor biomarkers cytokeratin 19 fragments (CYFRA 21-1) and carcinoembryonic antigen (CEA) as a potential predictor of benefit from adjuvant chemotherapy in early stage squamous cell carcinoma of the lung (SCC)

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The combination of the blood based tumor biomarkers cytokeratin 19 fragments (CYFRA 21-1) and carcinoembryonic antigen (CEA) as a potential predictor of benefit from adjuvant chemotherapy in early stage squamous cell carcinoma of the lung (SCC)

机译：血基肿瘤生物标志物细胞核酸素19片段（CYFRA 21-1）和癌胚抗原（CEA）的组合作为肺（SCC）早期鳞状细胞癌中辅助化疗的潜在预测因子

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Objectives: To determine whether the tumor biomarkers cytokeratin 19 fragment (CYFRA 21-1) and carcinoembryonic antigen (CEA), which are prognostic in early-stage non-small cell lung cancer (NSCLC), can predict which patients benefit from adjuvant chemotherapy (CTx).

机译：目的：确定肿瘤生物标志物细胞核病19片段（CYFRA 21-1）和甲基丙烯醛抗原（CEA），其在早期的非小细胞肺癌（NSCLC）中预后，可以预测哪些患者受益于佐剂化疗（ CTX）。

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来源
《Lung cancer: Journal of the International Association for the Study of Lung Cancer》 |2018年第2018期|共8页
作者
Muley Thomas; Rolny Vinzent; He Ying; Wehnl Birgit; Escherich Achim; Warth Arne; Stolp Christa; Schneider Marc A.; Dienemann Hendrik; Meister Michael; Herth Felix J.; Dayyani Farshid;
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作者单位

Univ Hosp Heidelberg Thoraxklin Translat Res Unit Heidelberg Germany;

Roche Diagnost GmbH Penzberg Germany;

Roche Diagnost GmbH Penzberg Germany;

Roche Diagnost GmbH Penzberg Germany;

Roche Diagnost Int Ltd Rotkreuz Switzerland;

German Ctr Lung Res DZL Translat Lung Res Ctr Heidelberg Germany;

Univ Hosp Heidelberg Thoraxklin Translat Res Unit Heidelberg Germany;

Univ Hosp Heidelberg Thoraxklin Translat Res Unit Heidelberg Germany;

German Ctr Lung Res DZL Translat Lung Res Ctr Heidelberg Germany;

Univ Hosp Heidelberg Thoraxklin Translat Res Unit Heidelberg Germany;

German Ctr Lung Res DZL Translat Lung Res Ctr Heidelberg Germany;

Roche Diagnost Int Ltd Rotkreuz Switzerland;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
NSCLC; Squamous cell carcinoma; CEA; CYFRA 21-1; Adjuvant chemotherapy; Prognosis;

机译：NSCLC;鳞状细胞癌;CEA;CYFRA 21-1;佐剂化疗;预后;

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1. The combination of the blood based tumor biomarkers cytokeratin 19 fragments (CYFRA 21-1) and carcinoembryonic antigen (CEA) as a potential predictor of benefit from adjuvant chemotherapy in early stage squamous cell carcinoma of the lung (SCC) [J] . Muley Thomas, Rolny Vinzent, He Ying, Lung cancer: Journal of the International Association for the Study of Lung Cancer . 2018,第期

机译：血基肿瘤生物标志物细胞核酸素19片段（CYFRA 21-1）和癌胚抗原（CEA）的组合作为肺（SCC）早期鳞状细胞癌中辅助化疗的潜在预测因子
2. P3.05-007 Potential of CYFRA 21-1 and CEA to Predict Adjuvant Chemotherapy Benefit in Early-Stage Squamous Cell Lung Cancer [J] . T. Muley, V. Rolny, Y. He, Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer . 2017,第11期

机译：P3.05-007 CyFRA 21-1和CEA的潜力预测早期鳞状细胞肺癌中的辅助化疗益处
3. Pro-gastrin-releasing peptide (ProGRP), neuron specific enolase (NSE), carcinoembryonic antigen (CEA) and cytokeratin 19-fragments (CYFRA 21-1) in patients with lung cancer in comparison to other lung diseases. [J] . Schneider J, Philipp M, Velcovsky HG, Anticancer Research: International Journal of Cancer Research and Treatment . 2003,第2Appa期

机译：与其他肺部疾病相比，肺癌患者的胃泌素释放肽（ProGRP），神经元特异性烯醇酶（NSE），癌胚抗原（CEA）和细胞角蛋白19片段（CYFRA 21-1）。
4. Subgroup analysis based on prognostic and predictive gene signatures for adjuvant chemotherapy in early-stage non-small-cell lung cancer patients [D] . Pluta, Dustin. 2015

机译：基于预后和预测基因特征的亚组分析用于早期非小细胞肺癌患者的辅助化疗
5. Decreased levels of serum cytokeratin 19 fragment CYFRA 21-1 predict objective response to chemotherapy in patients with non-small cell lung cancer [O] . LI PANG, JING WANG, YANWEN JIANG, -1

机译：血清细胞角蛋白19片段CYFRA 21-1的水平降低预示着非小细胞肺癌患者对化疗的客观反应
6. Comparison of cytokeratin fragment 19 (CYFRA 21-1), tissue polypeptide antigen (TPA) and carcinoembryonic antigen (CEA) as tumour markers in bronchogenic carcinoma [O] . Huang M.-S., Jong S.-B., Tsai M.-S., 1997

机译：细胞角蛋白片段19（CYFRA 21-1），组织多肽抗原（TPA）和癌胚抗原（CEA）作为支气管癌的肿瘤标志物的比较

The combination of the blood based tumor biomarkers cytokeratin 19 fragments (CYFRA 21-1) and carcinoembryonic antigen (CEA) as a potential predictor of benefit from adjuvant chemotherapy in early stage squamous cell carcinoma of the lung (SCC)

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