Changes in the incentive value of food after naltrexone treatment depend on a differential preference for a palatable food in male rats

摘要

Introduction: Opioid antagonist treatments such as naltrexone (NTX) and naloxone reduce consummatory behavior of palatable food (PF) and other incentives. Meanwhile, a significant increase in alcohol consumption has been observed when it is offered immediately after ending NTX treatment, an effect apparently produced by increased opioidergic activity caused by up-regulation of opioid receptors.Objective: On this basis we assessed changes in the consumption of PF after opioid antagonist treatment in rats with different preferences for that food.