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Two new diketopiperazines from the tin mine tailings-derived fungus Schizophyllum commune YIM DT 10058

机译:来自锡矿尾矿的两种新的二酮哌嗪 - 衍生的真菌精神术公社YIM DT 10058

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摘要

Two new diketopiperazines, named diphenylalazine C (1) and epicoccin U (2), together with six known compounds (3-8) were isolated from the EtOAc extract of the fermentation broth of the tin mine tailings-derived fungus Schizophyllum commune YIM DT 10058. Their structures were elucidated by detailed analysis of spectroscopic data and comparison with related known compounds. Compounds 1 and 2 exhibited weak antibacterial and cytotoxic activities.
机译:与锡矿尾矿发酵汤的EtOAc提取物中分离出两种新的二苯甲嗪c(1)和外杂菌素U(2),与六个已知的化合物(3-8)分离出锡矿尾矿尾矿的EtoAc提取物 - 衍生的真菌脑卒中的EtoAc提取物中分离出来的 。通过对光谱数据的详细分析并与相关已知化合物的比较来阐明它们的结构。 化合物1和2表现出弱抗菌和细胞毒性活性。

著录项

  • 来源
    《Natural product research》 |2017年第15期|共7页
  • 作者单位

    Yunnan Univ Key Lab Conservat &

    Utilizat Bioresource Minist Educ Yunnan Inst Microbiol Kunming;

    Yunnan Univ Key Lab Conservat &

    Utilizat Bioresource Minist Educ Yunnan Inst Microbiol Kunming;

    Yunnan Univ Minist Educ Key Lab Med Chem Nat Resource Kunming Peoples R China;

    Yunnan Univ Key Lab Conservat &

    Utilizat Bioresource Minist Educ Yunnan Inst Microbiol Kunming;

    Yunnan Univ Key Lab Conservat &

    Utilizat Bioresource Minist Educ Yunnan Inst Microbiol Kunming;

    Yunnan Univ Key Lab Conservat &

    Utilizat Bioresource Minist Educ Yunnan Inst Microbiol Kunming;

    Yunnan Univ Key Lab Conservat &

    Utilizat Bioresource Minist Educ Yunnan Inst Microbiol Kunming;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 药学;
  • 关键词

    Schizophyllum commune; diketopiperazines; antibacterial and cytotoxic activities;

    机译:Schizophyllum Commune;Diketopiperazines;抗菌和细胞毒性活动;

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