Chemical composition and antibacterial activity of Tussilago farfara (L.) essential oil from Quebec, Canada

摘要

The chemical composition of Tussilago farfara L. essential oil from the Saguenay-Lac-St-Jean region of Quebec, Canada was analyzed by gas chromatography-flame ionisation detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS), and the antibacterial activity of the oil was tested against Escherichia coli and Staphylococcus aureus. Forty-five (45) compounds were identified from the GC profile. The main components were 1-nonene (40.1%), alpha-phellandrene (26.0%) and rho-cymene (6.6%). The essential oil demonstrated antibacterial activity against E. coli (MIC50 = 468 mu g center dot mL(-1); MIC90 = 6869 mu g center dot mL(-1)) and S. aureus (MIC50 = 368 mu g center dot mL(-1); MIC90 = 773 mu g center dot mL(-1)). Dodecanoic acid was found to be active against both bacteria having a MIC50 and MIC90 of 16.4 mu g center dot mL(-1) and 95 mu g center dot mL(-1), respectively for E. coli and a MIC50 and MIC90 of 9.8 mu g center dot mL(-1) and 27.3 mu g center dot mL(-1), respectively for S. aureus. In addition, 1-decene and (E)-cyclodecene were also found to be active against E. coli.