Spatial Structure and Antimicrobial Activity of Cyclopropane Derivative of Limonene

摘要

A cyclopropane derivative of limonene, (IS, 4S, 6R)-7,7-dichloro-4-[(1S)-2,2-dichloro-l-methylcyclopropyl]-1-methylbicyclo [4.1.0] heptane (compound 2), was synthesized and its structure was determined by NMR and X-ray crystallographic methods. In addition, an antimicrobial activity of the compound against Gram-positive (Staphylococcus aureus, Bacillus subtilis) and Gram-negative (Escherichia coli, Pseudomonas aerziginosa) bacterial strains was also scrutinized.