Both in vivo FSH depletion and follicular exposure to Gonadotrophin-releasing hormone analogues in vitro are not effective to prevent follicular depletion during chemotherapy in mice

Horicks F.; Van den Steen G.; Gervy C.; Clarke H. J.; Demeestere I.

首页> 外文期刊>Molecular human reproduction. >Both in vivo FSH depletion and follicular exposure to Gonadotrophin-releasing hormone analogues in vitro are not effective to prevent follicular depletion during chemotherapy in mice

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Both in vivo FSH depletion and follicular exposure to Gonadotrophin-releasing hormone analogues in vitro are not effective to prevent follicular depletion during chemotherapy in mice

机译：在体外体内FSH耗尽和滤泡暴露于促性腺培养蛋白 - 释放激素类似物，不能有效地防止在小鼠中化疗期间的滤泡耗尽

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STUDY QUESTION: Does fertility preservation using gonadotrophin-releasing hormone (GnRH) analogues during chemotherapy act through a direct effect on the ovary or through inhibition of FSH secretion?

机译：研究问题：在化疗过程中使用促性腺培养蛋白酶（GnRH）类似物的生育能量通过直接影响卵巢或通过对FSH分泌的抑制作用？

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《Molecular human reproduction.》 |2018年第4期|共12页
作者
Horicks F.; Van den Steen G.; Gervy C.; Clarke H. J.; Demeestere I.;
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作者单位

Univ Libre Bruxelles Res Lab Human Reprod 808 Route Lennik B-1070 Brussels Belgium;

Univ Libre Bruxelles Res Lab Human Reprod 808 Route Lennik B-1070 Brussels Belgium;

Erasme Univ Hosp Lab Chem 808 Route Lennik B-1070 Brussels Belgium;

McGill Univ Dept Obstet Glen Res Bldg 1001 Decarie Blvd Montreal PQ H4A 3J1 Canada;

Univ Libre Bruxelles Res Lab Human Reprod 808 Route Lennik B-1070 Brussels Belgium;

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原文格式 PDF
正文语种 eng
中图分类呼吸生理;
关键词
cyclophosphamide; FSH; GnRH analogues; fertility preservation; apoptosis;

机译：环磷酰胺;fsh;gnrh类似物;生育保存;细胞凋亡;

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1. Both in vivo FSH depletion and follicular exposure to Gonadotrophin-releasing hormone analogues in vitro are not effective to prevent follicular depletion during chemotherapy in mice [J] . Horicks F., Van den Steen G., Gervy C., Molecular human reproduction. . 2018,第4期

机译：在体外体内FSH耗尽和滤泡暴露于促性腺培养蛋白 - 释放激素类似物，不能有效地防止在小鼠中化疗期间的滤泡耗尽
2. FSH prevents depletion of the resting follicle pool by promoting follicular number and morphology in fresh and cryopreserved primate ovarian tissues following xenografting [J] . Viktoria von Sch?nfeldt, Ramesh Chandolia, Robert Ochsenkühn, Reproductive Biology and Endocrinology . 2012,第1期

机译：FSH通过促进异种移植后新鲜的和冷冻保存的灵长类卵巢组织中的卵泡数目和形态来防止静息卵泡池的消耗
3. Effects of GnRH agonists on the expression of developmental follicular anti-mullerian hormone in varying follicular stages in cyclic mice in vivo [J] . Huang Jiliang, Wang Xiaoyan, Li Zhiling, Molecular medicine reports . 2015,第3aPta2期

机译：GnRH激动剂对体内不同周期卵泡发育阶段卵泡抗苗勒管激素表达的影响
4. Study on the growth of oocytes and steroidogenesis of granulosa cells in cattle: Effects of bone morphogenetic protein-4, follicle stimulating hormone and antral follicle count in ovaries on in vitro and in vivo follicular development [D] . 坂口, 謙一郎 2019

机译：牛卵母细胞生长和颗粒细胞类固醇生成的研究：卵巢中骨形态发生蛋白4，卵泡刺激素和胃窦卵泡计数对体内和体外卵泡发育的影响
5. FSH prevents depletion of the resting follicle pool by promoting follicular number and morphology in fresh and cryopreserved primate ovarian tissues following xenografting [O] . Viktoria von Schönfeldt, Ramesh Chandolia, Robert Ochsenkühn, 2012

机译：FSH通过促进异种移植后新鲜的和冷冻保存的灵长类卵巢组织中的卵泡数目和形态来防止静息卵泡池的消耗
6. FSH prevents depletion of the resting follicle pool by promoting follicular number and morphology in fresh and cryopreserved primate ovarian tissues following xenografting [O] . Schönfeldt V. (Viktoria) von, Chandolia R. (Ramesh), Ochsenkühn R. (Robert), 2013

机译：FSH通过促进异种移植后新鲜的和冷冻保存的灵长类卵巢组织中的卵泡数目和形态来防止静息卵泡池的消耗

Both in vivo FSH depletion and follicular exposure to Gonadotrophin-releasing hormone analogues in vitro are not effective to prevent follicular depletion during chemotherapy in mice

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