Clinical Evaluation of IntelliPlex (TM) KRAS G12/13 Mutation Kit for Detection of KRAS Mutations in Codon 12 and 13: A Novel Multiplex Approach

Chen Chi-Long; Chen Chi-Kuan; Ho Chung-Liang; Chi Wei-Ming; Yeh Chien-Hsuan; Hu Shian-Pin; Friebe Peter; Palmer Stuart; Huang Chin-Shiou

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Clinical Evaluation of IntelliPlex (TM) KRAS G12/13 Mutation Kit for Detection of KRAS Mutations in Codon 12 and 13: A Novel Multiplex Approach

机译：用于检测密码子12和13中KRAS突变检测的智能化（TM）KRAS G13突变试剂盒的临床评价：一种新型多重方法

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Background Colorectal cancer (CRC) is among the most frequently occurring cancers worldwide and its incidence is forecasted to increase. Testing for KRAS (Kirsten rat sarcoma viral oncogene homolog) mutations in colorectal tissue biopsy samples has become a crucial tool to guide therapeutic decisions for personalized treatment.

机译：背景，结直肠癌（CRC）是全球最常见的癌症之一，其发病率预测增加。结直肠组织活检样品中的KRAs（Kirsten大鼠肉瘤病毒癌症同源物）突变已成为指导个性化治疗的治疗决策的重要工具。

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《Molecular diagnosis & therapy》 |2019年第5期|共12页
作者
Chen Chi-Long; Chen Chi-Kuan; Ho Chung-Liang; Chi Wei-Ming; Yeh Chien-Hsuan; Hu Shian-Pin; Friebe Peter; Palmer Stuart; Huang Chin-Shiou;
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作者单位

Wan Fang Hosp Dept Pathol Taipei Taiwan;

MacKay Mem Hosp Dept Pathol Taipei Taiwan;

Natl Cheng Kung Univ Hosp Dept Pathol Tainan Taiwan;

Taipei Med Univ Shuang Ho Hosp Dept Lab Med Taipei Taiwan;

PlexBio Co Ltd 6F-16 1 351 Yangguang St Taipei 11491 Taiwan;

PlexBio Co Ltd 6F-16 1 351 Yangguang St Taipei 11491 Taiwan;

PlexBio Co Ltd 6F-16 1 351 Yangguang St Taipei 11491 Taiwan;

PlexBio Co Ltd 6F-16 1 351 Yangguang St Taipei 11491 Taiwan;

PlexBio Co Ltd 6F-16 1 351 Yangguang St Taipei 11491 Taiwan;

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原文格式 PDF
正文语种 eng
中图分类临床医学;
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入库时间 2022-08-20 04:12:02

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专利

1. Clinical Evaluation of IntelliPlex (TM) KRAS G12/13 Mutation Kit for Detection of KRAS Mutations in Codon 12 and 13: A Novel Multiplex Approach [J] . Chen Chi-Long, Chen Chi-Kuan, Ho Chung-Liang, Molecular diagnosis & therapy . 2019,第5期

机译：用于检测密码子12和13中KRAS突变检测的智能化（TM）KRAS G13突变试剂盒的临床评价：一种新型多重方法
2. High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer [J] . Michael Krypuy, Genni M Newnham, David M Thomas, BMC Cancer . 2006,第1期

机译：高分辨率熔解分析可快速灵敏地检测临床样本中的突变：非小细胞肺癌中的KRAS密码子12和13突变
3. Sensitive multiplex detection of KRAS codons 12 and 13 mutations in paraffin-embedded tissue specimens [J] . Walairat Laosinchai-Wolf, Fei Ye, Vu Tran, Journal of Clinical Pathology . 2011,第1期

机译：灵敏的多重检测石蜡包埋的组织标本中的KRAS密码子12和13突变
4. Isolation of Circulating Tumor Cells from Patients with Metastatic Colorectal Cancer Using Label-Free Microfluidic Technology for Enumeration and Detection of KRAS, BRAF, PIK3CA Mutation [C] . Haiyan Emily Liu, Evelyn Kidess-Sigal, Melanie Triboulet, International Molecular Medicine Tri-Conference. . 2016

机译：使用无标记微流体技术分离转移性结肠直肠癌患者的循环肿瘤细胞进行募准和检测KRA，BRAF，PIK3CA突变
5. High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer [O] . Michael Krypuy, Genni M Newnham, David M Thomas, 2006

机译：高分辨率熔解分析可快速灵敏地检测临床样品中的突变：非小细胞肺癌中的KRAS密码子12和13突变
6. High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer [O] . Thomas David M, Newnham Genni M, Krypuy Michael, 2006

机译：高分辨率熔解分析，用于快速，灵敏地检测临床样本中的突变： KRas 密码子12和13突变非小细胞肺癌

Clinical Evaluation of IntelliPlex (TM) KRAS G12/13 Mutation Kit for Detection of KRAS Mutations in Codon 12 and 13: A Novel Multiplex Approach

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