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首页> 外文期刊>Molecular biology reports >The application of gene marker-assisted selection and proteomics for the best meat quality criteria and body measurements in Qinchuan cattle breed
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The application of gene marker-assisted selection and proteomics for the best meat quality criteria and body measurements in Qinchuan cattle breed

机译:基因标志物辅助选择和蛋白质组学在秦川牛种类中的最佳肉质标准和身体测量中的应用

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摘要

In the past few decades, enhancement of animal productivity has been gaining increasing attention among decisions-makers, politicians, mangers, and breeders, because of the increasing of world population and shortage of natural resources. The selection of high productivity animals is the main goal, through the application of genetic improvement programs. The use of molecular genetics has conferred significant breeding advantages over conventional breeding techniques. In this regard, many economic characteristics are controlled by a small number of multiple gene loci, each of which is responsible for trait diversity and hence they are referred to as quantitative trait loci (QTL). Single-nucleotide polymorphisms (SNPs), which have recently been discovered through DNA sequencing, are considered one of the most useful types of genetic marker. SNPs are found where different nucleotides occur at the same position in the DNA sequence. They are found in both coding and noncoding regions of the genome and are present at one SNP in every 1000 b. Strategies for the identification and application of markers are based on reference to examples of loci that can control various traits. Furthermore, markers for growth, body measurements, and meat quality traits are preferred, because they can be used to predict the performance of animals, via blood samples, in the first few days of animal life. Marker-assisted selection using SNPs, such asSIRT1, SIRT2, LPL, CRTC2, SIX4, UCPs, and ZBTB38as selection criteria of body measurements and meat traits in beef cattle, will be beneficial in selection and breeding programs. The proteomic is a novel marker and a new approache of biotechnology which increases the understanding of the biological processes, besides being a remarkable biomarker that interrelated to growth and meat quality traits. Proteomics is a vigorous tool as usage for deduces molecular processes between quality traits and muscle proteins, which are helpful in analyzing the mechanisms of biochemistry that influence quality. So they could be potential biomarker for some meat quality traits. Among them, Actin, Myosin, Heat shock proteins are used a novel approaches in the field of biotechnology to understand the proteomics changes. This review article highlights the novel findings on the potential use of MAS and proteomics as biomarker for the selection for meat quality and carcass traits in Qinchuan cattle breed.
机译:在过去的几十年里,由于世界人口的增加和自然资源短缺,增加了动物生产力的提高越来越多地受到越来越关注的决定制造者,政治家,人工人员和育种者。通过应用遗传改善计划,选择高生产率的动物是主要目标。分子遗传学的使用赋予常规育种技术的显着育种优点。在这方面,许多经济特征是由少量多基因基因座控制的,每个经济特征负责性状多样性,因此它们被称为定量性状基因座(QTL)。最近通过DNA测序发现的单核苷酸多态性(SNP)被认为是最有用类型的遗传标记之一。发现SNPS在DNA序列中发生不同的核苷酸在相同位置发生。它们存在于基因组的编码和非编码区域中,并且在每1000b中存在于一个SNP。标记识别和应用的策略基于对可以控制各种特征的基因座的示例参考。此外,优选用于生长,身体测量和肉质性状的标志物,因为它们可用于通过血液样本在动物生命的前几天预测动物的性能。使用SNP的标记辅助选择,例如BEEF牛身体测量和肉类特征的SUSIRT1,SIRT2,LPL,CRTC2,SIMP38,UCP和ZBTB38AS选择标准将是有益的选择和育种计划。蛋白质组学是一种新的标记和生物技术的新方法,这增加了对生物过程的理解,除了是一种非凡的生物标志物,可相互关联于生长和肉质性状。蛋白质组学是一种剧烈的工具,用作推出质量性状和肌肉蛋白质之间的分子过程,这有助于分析影响质量的生物化学机制。因此,它们可能是一些肉质性状的潜在生物标志物。其中,肌动蛋白,肌球蛋白,热休克蛋白在生物技术领域中使用了一种新的方法,以了解蛋白质组学的变化。该综述文章突出了关于潜在使用MAS和蛋白质组学作为生物标志物的新调查结果,用于秦川牛种类的肉质和胴体性状。

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