Risk of Suicidal Behavior With Use of Efavirenz: Results from the Strategic Timing of Antiretroviral Treatment Trial

Arenas-Pinto Alejandro; Grund Birgit; Sharma Shweta; Martinez Esteban; Cummins Nathan; Fox Julie; Klingmau Karin L.; Sedlacek Dalibor; Collins Simon; Flynn Patricia M.; Chasanov William M.; Kedem Eynat; Katlama Christine; Sierra-Madero Juan; Afonso Claudia; Brouwers Pim; Cooper David A.

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Risk of Suicidal Behavior With Use of Efavirenz: Results from the Strategic Timing of Antiretroviral Treatment Trial

机译：使用efavirazenz的自杀行为风险：抗逆转录病毒治疗试验的战略时机的结果

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Background. Randomized trials have shown increased risk of suicidality associated with efavirenz (EFV). The START (Strategic Timing of Antiretroviral Treatment) trial randomized treatment-naive human immunodeficiency virus (HIV)-positive adults with high CD4 cell counts to immediate vs deferred antiretroviral therapy (ART).

机译：背景。随机试验表明与efaviraz（EFV）相关的自由性的风险增加。开始（抗逆转录病毒治疗的战略时序）试验随机治疗 - 幼稚人免疫缺陷病毒（HIV） - 具有高CD4细胞的阳性成人，对即时VS延迟抗逆转录病毒治疗（ART）。

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来源
《Fortschritte der Physik》 |2018年第3期|共10页
作者
Arenas-Pinto Alejandro; Grund Birgit; Sharma Shweta; Martinez Esteban; Cummins Nathan; Fox Julie; Klingmau Karin L.; Sedlacek Dalibor; Collins Simon; Flynn Patricia M.; Chasanov William M.; Kedem Eynat; Katlama Christine; Sierra-Madero Juan; Afonso Claudia; Brouwers Pim; Cooper David A.;
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作者单位

UCL Med Res Council Trials Unit London England;

Univ Minnesota Sch Stat Minneapolis MN 55455 USA;

Univ Minnesota Div Biostat Minneapolis MN USA;

Hosp Clin Barcelona Barcelona Spain;

Mayo Clin Rochester MN USA;

Guys &

St Thomas NHS Fdn Trust London England;

NIAID Div Aids NIH Bethesda MD 20892 USA;

Univ Hosp Plzen Plzen Czech Republic;

HIV I Base London England;

St Jude Childrens Res Hosp 332 N Lauderdale St Memphis TN 38105 USA;

Cooper Univ Hosp Camden NJ USA;

Rambam Hlth Care Ctr Clin Immunol Unit Haifa Israel;

Hosp Pitie Salpetriere Paris France;

Inst Nacl Ciencias Med &

Nutr Salvador Zubiran Tlalpan Mexico;

Hosp Santa Maria Lisbon Portugal;

NIAID Div Aids NIH Bethesda MD 20892 USA;

Univ New South Wales Kirby Inst Sydney NSW Australia;

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原文格式 PDF
正文语种 eng
中图分类物理学;
关键词
HIV; suicidal behavior; efavirenz;

机译：艾滋病毒;自杀行为;efaviraz;

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专利

1. Risk of Suicidal Behavior With Use of Efavirenz: Results from the Strategic Timing of Antiretroviral Treatment Trial [J] . Arenas-Pinto Alejandro, Grund Birgit, Sharma Shweta, Fortschritte der Physik . 2018,第3期

机译：使用efavirazenz的自杀行为风险：抗逆转录病毒治疗试验的战略时机的结果
2. Prevalence of and risk factors for low bone mineral density in untreated HIV infection: a substudy of the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial [J] . Carr A., Grund B., Neuhaus J., HIV medicine . 2015,第Suppla1期

机译：未经治疗的HIV感染中骨矿物质密度低的患病率和危险因素：抗逆转录病毒疗法（START）试验的INSIGHT战略时机的子研究
3. Transmission risk behaviour at enrolment in participants in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial [J] . Rodger A. J., Lampe F. C., Grulich A. E., HIV medicine . 2015,第Suppla1期

机译：参加INSIGHT抗逆转录病毒治疗战略时机（START）试验的参与者的传播风险行为
4. The Two First-Line Recommended Antiretroviral Regimens for Naive HIV-Infected Patients: Efavirenz-Based Versus Lopinavir-Ritonavir-Based Haart [C] . R. Manfredi, L. Calza, F. Chiodo International AIDS Conference . 2004

机译：幼稚艾滋病毒感染患者的两种第一线推荐的抗逆转录病毒方案：efavirenz为基于Lopinavir-Ritonavir的HAART
5. Validation of a UPLC-MS/MS method for the simultaneous measurement of the antiretroviral drugs atazanavir, darunavir, efavirenz, etravirine, lopinavir, raltegravir, ritonavir from human plasma. [D] . Patel, Rutva. 2012

机译：用于从人血浆中同时测定抗逆转录病毒药物阿扎那韦，达鲁那韦，依非韦伦，依曲韦林，洛匹那韦，拉格列韦，利托那韦的UPLC-MS / MS方法的验证。
6. Risk of Suicidal Behavior With Use of Efavirenz: Results from the Strategic Timing of Antiretroviral Treatment Trial [O] . Alejandro Arenas-Pinto, Birgit Grund, Shweta Sharma, -1

机译：使用依法韦仑引起自杀行为的风险：抗逆转录病毒治疗试验的战略时机结果
7. Transmission risk behaviour at enrolment in participants in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial [O] . Rodger, A, Lampe, F, Grulich, A, 2015

机译：INSIGHT抗逆转录病毒治疗的战略时机（START）试验参与者的传播风险行为

Risk of Suicidal Behavior With Use of Efavirenz: Results from the Strategic Timing of Antiretroviral Treatment Trial

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