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Maturation from CoreValve ? to Evolut Pro ? : a clinical overview

机译:核心风格成熟? evolut pro? :临床概述

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摘要

The only curative treatment of aortic stenosis is through surgical or transcatheter aortic valve replacement. Transcatheter aortic valve implantation has evolved from its first in human experience in 2002 and matured to the treatment of first choice of symptomatic severe aortic stenosis in elderly patients with an elevated operative risk. The self-expanding CoreValve~(?) bioprosthesis has been on the forefront of this growing transcatheter aortic valve implantation experience. Over the last decade, various device iterations resulted in the current Evolut PRO~(?) self-expanding valve platform with reduced profile, repositioning/retrievable features and porcine pericardial wrap. Herein we provide a critical appraisal of the consecutive device iterations and highlight the clinical foundation for the use of the self-expanding CoreValve~(?) /Evolut platforms in current clinical practice.
机译:主动脉狭窄的唯一疗法治疗是通过手术或经膜状管主动脉瓣置换。 经沟管主动脉瓣植入从2002年首次演变,并成熟,以治疗老年患者患者风险较高的患者症状严重主动脉狭窄的首选。 自我扩张的CoreValve〜(?)生物假体已经处于这种不断增长的经齿轮管主动脉瓣植入体验的最前沿。 在过去十年中,各种设备迭代导致当前的Evolut Pro〜(?)自扩张阀平台,具有减少的轮廓,重新定位/可检索的特征和猪心包包装。 在此,我们提供了连续设备迭代的关键评估,并突出了在当前临床实践中使用自我扩张的核心Valve〜(?)/ Evolut平台的临床基础。

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