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机译:癌症中的种系和体细胞突变:专注于缺陷的DNA修复,PARP抑制剂和免疫疗法
Department of Pathological Anatomy Polytechnic University of the Marche Region School of Medicine;
Department of PathologyandSurgery Faculty of Medicine;
Department of Oncology S. Orsola-Malpighi Hospital;
Department of Oncology Macerata Hospital;
Department of Pathological Anatomy Polytechnic University of the Marche Region School of Medicine;
Department of Pathological Anatomy Polytechnic University of the Marche Region School of Medicine;
Department of Urology Polytechnic University of the Marche Region United Hospitals;
Department of PathologyandLaboratory Medicine Indiana University School of Medicine;
Department of Pathological Anatomy Polytechnic University of the Marche Region School of Medicine;
BRCA1; BRCA2; defective DNA repair; immunotherapy; PARP inhibitors; prostate cancer;
机译:癌症中的种系和体细胞突变:专注于缺陷的DNA修复,PARP抑制剂和免疫疗法
机译:双等位基因的体细胞肿瘤突变解释了大肠和子宫内膜癌病例,其中有不匹配的缺损修复或没有可识别的种系突变或MLH1表观遗传沉默
机译:PARP抑制剂在去势抵抗性前列腺癌中获得FDA突破性治疗指定:超越种系BRCA突变
机译:FAP和散发性大肠癌中APC基因的种系和体细胞突变以及基因型-表型分析
机译:在以人群为基础的早发性大肠癌患者样本中预测定量模型预测Lynch综合征(遗传性非息肉病性大肠直肠癌,DNA失配修复缺陷)的准确性
机译:拉丁美洲乳腺癌DNA修复基因中生殖系突变的景观:类似于PARP的抑制剂和免疫疗法的机会
机译:前列腺癌中的种系和体细胞突变:专注于缺陷DNA修复,PARP抑制剂和免疫疗法